Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7351947 | 0.91 | KMT2A (0.56) | KMT2ACA12CA9CA1CA2 | |
| SCHEMBL8592201 | 0.91 | CA2 (0.57) | KMT2ACA12CA9CA1CA2 | |
| SCHEMBL11707958 | 0.89 | KMT2A (0.83) | KMT2ACA12CA9CA1CA2 | |
| SCHEMBL3386980 | 0.88 | ATM (0.66) | KMT2ACA12CA9CA1CA2 | |
| SCHEMBL3713687 | 0.88 | KMT2A (0.56) | KMT2ACA12CA9CA1CA2 | |
| SCHEMBL301798 | 0.86 | ALDH1A1 (0.68) | CA12CA9CA1CA2ALDH1A1 | |
| SCHEMBL14674435 | 0.85 | KMT2A (0.53) | KMT2ACA12CA9CA1CA2 | |
| SCHEMBL21726734 | 0.85 | KMT2A (0.53) | KMT2ACA12CA9CA1CA2 | |
| SCHEMBL16775756 | 0.85 | KMT2A (0.53) | KMT2ACA12CA9CA1CA2 | |
| Hydrochloric Acid SCHEMBL7362553 | 0.84 | ALDH1A1 (0.66) | CA12CA9CA1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9120819-B2 | FGF-receptor agonist dimeric compounds | SANOFI (FR) | 2015-09-01 | — | — | US | disclosed |