Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11000181 | 0.77 | DAO (0.47) | DAOSLC6A3TP53HCAR3HCAR2 | |
| SCHEMBL4507146 | 0.71 | L3MBTL1 (0.50) | KMT2ASLC6A3SLC6A2SLC6A4L3MBTL1 | |
| SCHEMBL5487986 | 0.70 | SLC6A3 (0.57) | SLC6A3SLC6A2SMN1; SMN2SLC6A4 | |
| SCHEMBL25308367 | 0.69 | DAO (0.39) | DAOKMT2AKAT2BSLC6A3NPC1 | |
| SCHEMBL1526022 | 0.68 | KMT2A (0.64) | KMT2ASLC6A3SLC6A2MEN1SLC6A4 | |
| SCHEMBL19127835 | 0.67 | DAO (0.59) | DAOKMT2AKAT2BTP53MEN1 | |
| SCHEMBL4779827 | 0.67 | L3MBTL1 (0.49) | KMT2ATP53MEN1SMN1; SMN2HPGD | |
| Propane SCHEMBL27580660 | 0.67 | L3MBTL1 (0.50) | SLC6A3SLC6A2SMN1; SMN2SLC6A4L3MBTL1 | |
| SCHEMBL908518 | 0.66 | HDAC3 (0.44) | KMT2AMEN1NPC1RAB9AMAPK1 | |
| SCHEMBL187559 | 0.66 | CYP2C19 (0.52) | KMT2ASMN1; SMN2HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002846-B1 | 3-THIENYLMALONIC ACIDS, THE CORRESPONDING DIESTERS AND THEIR PREPARATION | Océ-Andeno B.V. (NL) | 1984-05-23 | — | — | EP | disclosed |
| US-4262129-A | Preparation of a 3-thienylmalonic acid and the corresponding diesters | OCE-ANDENO B.V. (NL) | 1981-04-14 | — | — | US | disclosed |