Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | SLC8B1 | Q6J4K2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11087922 | 0.81 | TSHR (0.41) | MAPTTSHRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10929981 | 0.77 | MAPT (0.77) | MAPTTSHRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10929004 | 0.72 | MAPT (0.56) | MAPTTSHRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10367113 | 0.71 | HDAC3 (0.57) | MAPTTSHRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11081504 | 0.70 | ALDH1A1 (0.44) | MAPTTSHRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL31071906 | 0.68 | TP53 (1.00) | MAPTTSHRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL869274 | 0.68 | TP53 (1.00) | MAPTTSHRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10926019 | 0.67 | MAPT (0.60) | MAPTTSHRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6364379 | 0.65 | KMT2A (0.46) | MAPTTSHRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9659046 | 0.64 | KMT2A (0.70) | MAPTTSHRCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4464300-A | PSYCHOTROPIC, ANXIOLYTIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1984-08-07 | — | — | US | disclosed |