Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | GPR183 | P32249 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | PHGDH | O43175 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11080880 | 1.00 | RAB9A (0.55) | RAB9ANPC1ALDH1A1LMNAMGLL | |
| SCHEMBL6509083 | 0.82 | RAB9A (0.54) | RAB9ANPC1ALDH1A1LMNAMAPT | |
| SCHEMBL6509077 | 0.82 | RAB9A (0.54) | RAB9ANPC1ALDH1A1LMNAMAPT | |
| SCHEMBL22230800 | 0.82 | GPR183 (0.43) | RAB9ANPC1ALDH1A1GPR183SMN1; SMN2 | |
| SCHEMBL22230801 | 0.82 | GPR183 (0.43) | RAB9ANPC1ALDH1A1GPR183SMN1; SMN2 | |
| SCHEMBL10410292 | 0.81 | L3MBTL1 (0.55) | RAB9ANPC1ALDH1A1LMNAMGLL | |
| SCHEMBL10410291 | 0.81 | L3MBTL1 (0.55) | RAB9ANPC1ALDH1A1LMNAMGLL | |
| SCHEMBL31547242 | 0.81 | RAB9A (0.43) | RAB9ANPC1ALDH1A1LMNAGPR183 | |
| SCHEMBL28121251 | 0.72 | RAB9A (0.47) | RAB9ANPC1ALDH1A1LMNAMAPT | |
| SCHEMBL9222171 | 0.71 | GAA (0.48) | RAB9ANPC1ALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0022906-B1 | PROCESS FOR THE PREPARATION OF PYRAZOLE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-08-08 | — | — | EP | disclosed |
| EP-0022906-A1 | Process for the preparation of pyrazole derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-01-28 | — | — | EP | disclosed |