Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11080951 | 1.00 | POLB (0.65) | POLBCYP11B1CYP11B2MAPTCYP1A2 | |
| SCHEMBL8303787 | 1.00 | POLB (0.65) | POLBCYP11B1CYP11B2MAPTCYP1A2 | |
| SCHEMBL2805466 | 0.82 | POLB (0.53) | POLBMAPTCYP1A2HPGDALOX12 | |
| SCHEMBL11066346 | 0.82 | POLB (0.53) | POLBMAPTHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL11066332 | 0.82 | POLB (0.53) | POLBMAPTHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL2805463 | 0.82 | POLB (0.53) | POLBMAPTCYP1A2HPGDALOX12 | |
| SCHEMBL11076121 | 0.82 | POLB (0.53) | POLBMAPTHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL1239325 | 0.81 | POLB (0.51) | POLBMAPTCYP1A2HPGDSMN1; SMN2 | |
| SCHEMBL11083067 | 0.81 | POLB (0.51) | POLBHPGDSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL11083064 | 0.81 | POLB (0.51) | POLBHPGDSMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022144274-A1 | NOVEL GALACTOSIDE INHIBITOR OF GALECTINS | GALECTO BIOTECH AB (DK) | 2022-07-07 | — | — | WO | disclosed |
| EP-0478195-B1 | Dihydropyridazinones and pyridazinones as fungicides | ROHM & HAAS (US) | 1999-05-26 | — | — | EP | disclosed |
| US-5753642-A | AGRICULTURE, MEDICINE | ROHM AND HAAS COMPANY (US) | 1998-05-19 | — | — | US | disclosed |
| US-5728715-A | FOR MAMMALS, AGRICULTURE, RICE, WHEAT, TOMATOES | ROHM AND HAAS COMPANY (US) | 1998-03-17 | — | — | US | disclosed |
| US-5728698-A | AGRICULTURAL USE, RICE, WHEAT | ROHM AND HAAS COMPANY (US) | 1998-03-17 | — | — | US | disclosed |
| US-5728694-A | Dihydropyridazinones, pyridazinones and related compounds as fungicides | ROHM AND HAAS COMPANY (US) | 1998-03-17 | — | — | US | disclosed |
| US-5726176-A | FOR CONTROLLING AGRICULTURAL AND MAMMALIAN FUNGAL DISEASES | ROHM AND HAAS COMPANY (US) | 1998-03-10 | — | — | US | disclosed |
| US-5726162-A | FOR CONTROLLING AGRICULTURAL AND MAMMALIAN FUNGAL DISEASES | ROHM AND HAAS COMPANY (US) | 1998-03-10 | — | — | US | disclosed |
| US-5631254-A | RICE; HUMAN INFECTIONS | ROHM AND HAAS COMPANY (US) | 1997-05-20 | — | — | US | disclosed |
| US-5552409-A | PHYTOPATHOGENIC, RICE | ROHM AND HAAS COMPANY (US) | 1996-09-03 | — | — | US | disclosed |
| US-4473395-A | Method for inducing tillering utilizing certain pyridine-1-oxides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-09-25 | — | — | US | disclosed |
| US-4405552-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1983-09-20 | — | — | US | disclosed |
| EP-0017438-B1 | SUBSTITUTED 3-ALKYL-6-PHENYL-1,2,4-TRIAZOLO(4,3-A)PYRIDINES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AMERICAN CYANAMID COMPANY (US) | 1983-03-02 | — | — | EP | disclosed |
| EP-0067511-A2 | Method of inducing tillering using pyridine derivatives, and some of the pyridines themselves, process for preparing them and agricultural compositions containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-12-22 | — | — | EP | disclosed |
| US-4351843-A | LOWERING BLOOD GLUCOSE | PFIZER INC. (US) | 1982-09-28 | — | — | US | disclosed |
| EP-0060071-A1 | Improvements in or relating to 1-benzoyl-3-(arylpyridyl)urea compounds | ELI LILLY AND COMPANY (US) | 1982-09-15 | — | — | EP | disclosed |
| US-4282242-A | HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1981-08-04 | — | — | US | disclosed |
| US-4242515-A | Substituted 3-alkyl-6-phenyl-1,2,4-triazolo-[4,3-a]pyridines | AMERICAN CYANAMID COMPANY (US) | 1980-12-30 | — | — | US | disclosed |
| EP-0017438-A1 | Substituted 3-alkyl-6-phenyl-1,2,4-triazolo(4,3-a)pyridines, processes for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1980-10-15 | — | — | EP | disclosed |
| US-4209626-A | Substituted 6-phenyl-1,2,4-triazolo[4,3-a]pyridines | AMERICAN CYANAMID COMPANY (US) | 1980-06-24 | — | — | US | disclosed |