Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMO | Q99835 | 2/20 | 0.37 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.36 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11081247 | 0.72 | KMT2A (0.44) | KMT2AMEN1ALDH1A1DRD2DRD4 | |
| SCHEMBL11082068 | 0.71 | KMT2A (0.43) | KMT2AMEN1ALDH1A1DRD2DRD4 | |
| SCHEMBL13924866 | 0.70 | ERCC1 (0.50) | ALOX12KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL7922538 | 0.66 | TSHR (0.35) | KMT2AMEN1ALDH1A1POLBHPGD | |
| SCHEMBL6293317 | 0.65 | KMT2A (0.73) | KMT2AMEN1ALDH1A1POLBTSHR | |
| SCHEMBL13924876 | 0.65 | SMO (0.58) | ALOX12KMT2AMEN1DRD2DRD4 | |
| SCHEMBL13924879 | 0.65 | SMO (0.58) | ALOX12KMT2AMEN1DRD2DRD4 | |
| SCHEMBL17294178 | 0.64 | ALDH1A1 (0.62) | ALOX12KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL28548456 | 0.63 | CA12 (0.59) | KMT2AMEN1ALDH1A1POLBKDM4E | |
| SCHEMBL4692001 | 0.62 | MEN1 (0.47) | KMT2AMEN1ALDH1A1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4426522-A | ANTICOCCIDIAL | ABIC LTD. (IL) | 1984-01-17 | — | — | US | disclosed |
| EP-0058534-A2 | Hexahydro-1,2,4-triazine-3,5-dione derivatives and their use as feed additives | ABIC LTD. (IL) | 1982-08-25 | — | — | EP | disclosed |