Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | DBH | P09172 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.35 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11081247 | 0.98 | KMT2A (0.44) | KMT2AMEN1ALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL11075283 | 0.83 | SMN1; SMN2 (0.45) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL11085801 | 0.83 | DDB1 (0.51) | KMT2AMEN1ALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL11079756 | 0.83 | KMT2A (0.47) | KMT2AALDH1A1SIGMAR1MAPTDBH | |
| SCHEMBL11290437 | 0.81 | DBH (0.43) | KMT2AMEN1ALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL11089788 | 0.81 | MAPT (0.51) | KMT2AMEN1KDM4ESIGMAR1MAPT | |
| SCHEMBL11084167 | 0.80 | USP2 (0.43) | KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL11080183 | 0.80 | MEN1 (0.57) | KMT2AMEN1ALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL11285216 | 0.78 | SMN1; SMN2 (0.49) | KMT2AMEN1ALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL11079280 | 0.72 | KMT2A (0.51) | KMT2AMEN1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4426522-A | ANTICOCCIDIAL | ABIC LTD. (IL) | 1984-01-17 | — | — | US | claimed |
| EP-0058534-A2 | Hexahydro-1,2,4-triazine-3,5-dione derivatives and their use as feed additives | ABIC LTD. (IL) | 1982-08-25 | — | — | EP | claimed |
| US-4426522-A | ANTICOCCIDIAL | ABIC LTD. (IL) | 1984-01-17 | — | — | US | disclosed |
| EP-0058534-A2 | Hexahydro-1,2,4-triazine-3,5-dione derivatives and their use as feed additives | ABIC LTD. (IL) | 1982-08-25 | — | — | EP | disclosed |