Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.66 |
| ▸ | DRD4 | P21917 | 6/20 | 0.66 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.66 |
| ▸ | HTR1A | P08908 | 4/20 | 0.60 |
| ▸ | HTR2A | P28223 | 4/20 | 0.60 |
| ▸ | HTR2C | P28335 | 4/20 | 0.60 |
| ▸ | DRD3 | P35462 | 4/20 | 0.60 |
| ▸ | HRH1 | P35367 | 2/20 | 0.60 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.60 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.60 |
| ▸ | HTR7 | P34969 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11084263 | 0.99 | DRD2 (0.64) | DRD2DRD4SIGMAR1HTR1AHTR2A | |
| SCHEMBL7749833 | 0.87 | DRD2 (0.57) | DRD2DRD4SIGMAR1HTR1AHTR2A | |
| SCHEMBL7754509 | 0.87 | DRD2 (0.54) | DRD2DRD4SIGMAR1HTR1AHTR2A | |
| SCHEMBL7754649 | 0.87 | DRD2 (0.54) | DRD2DRD4SIGMAR1HTR1AHTR2A | |
| SCHEMBL7749851 | 0.87 | DRD2 (0.57) | DRD2DRD4SIGMAR1HTR1AHTR2A | |
| Bromide SCHEMBL7754529 | 0.86 | DRD2 (0.53) | DRD2DRD4SIGMAR1HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL7755991 | 0.86 | TSHR (0.54) | DRD2DRD4SIGMAR1HTR1AHTR2A | |
| SCHEMBL27494766 | 0.86 | DRD2 (0.53) | DRD2DRD4SIGMAR1HTR1AHTR2A | |
| SCHEMBL7755965 | 0.84 | DRD2 (0.56) | DRD2DRD4SIGMAR1HTR1AHTR2A | |
| SCHEMBL7754568 | 0.84 | SIGMAR1 (0.57) | DRD2DRD4SIGMAR1HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4452799-A | NEUROLEPTIC AGENTS | MEAD JOHNSON & COMPANY (US) | 1984-06-05 | — | — | US | claimed |
| US-4452799-A | NEUROLEPTIC AGENTS | MEAD JOHNSON & COMPANY (US) | 1984-06-05 | — | — | US | disclosed |
| US-4411901-A | ANTIPSYCHOTICS | MEAD JOHNSON & COMPANY (US) | 1983-10-25 | — | — | US | disclosed |