Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 6/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.45 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.45 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.45 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.42 |
| ▸ | VEGFA | P15692 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | TPMT | P51580 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2054426 | 0.81 | TSHR (0.58) | KIF11TSHRALDH1A1TDP1CYP3A4 | |
| SCHEMBL29659699 | 0.81 | TSHR (0.58) | KIF11TSHRALDH1A1TDP1CYP3A4 | |
| SCHEMBL11600925 | 0.80 | KIF11 (0.59) | KIF11TSHRALDH1A1TDP1CYP3A4 | |
| SCHEMBL11599104 | 0.80 | KIF11 (0.61) | KIF11TSHRALDH1A1TDP1CYP3A4 | |
| SCHEMBL11599131 | 0.80 | KIF11 (0.48) | KIF11TSHRALDH1A1TDP1CYP3A4 | |
| SCHEMBL11601182 | 0.80 | KIF11 (0.62) | KIF11TSHRALDH1A1TDP1CYP3A4 | |
| SCHEMBL29505103 | 0.79 | TSHR (0.42) | KIF11TSHRALDH1A1TDP1CYP3A4 | |
| SCHEMBL11600890 | 0.79 | KIF11 (0.60) | KIF11TSHRALDH1A1TDP1CYP3A4 | |
| SCHEMBL11601372 | 0.78 | KIF11 (0.54) | KIF11TSHRALDH1A1TDP1EPAS1 | |
| SCHEMBL10063513 | 0.77 | ALDH1A1 (0.49) | KIF11TSHRALDH1A1TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0031257-B1 | PYRIDYLANILINES | ISHIHARA SANGYO KAISHA LTD. (JP) | 1984-08-15 | — | — | EP | disclosed |
| US-4331670-A | PESTICIDES | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1982-05-25 | — | — | US | disclosed |
| EP-0031257-A2 | Pyridylanilines | ISHIHARA SANGYO KAISHA LTD. (JP) | 1981-07-01 | — | — | EP | disclosed |