Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 6/20 | 0.54 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | VEGFA | P15692 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11600925 | 0.87 | KIF11 (0.59) | KIF11EPAS1MAPTALDH1A1NPSR1 | |
| SCHEMBL11601182 | 0.87 | KIF11 (0.62) | KIF11EPAS1MAPTALDH1A1NPSR1 | |
| SCHEMBL9788483 | 0.83 | KIF11 (0.48) | KIF11EPAS1ALDH1A1KDM4ELMNA | |
| SCHEMBL11599104 | 0.82 | KIF11 (0.61) | KIF11EPAS1MAPTALDH1A1LMNA | |
| SCHEMBL11600890 | 0.81 | KIF11 (0.60) | KIF11EPAS1MAPTALDH1A1LMNA | |
| SCHEMBL11082077 | 0.78 | KIF11 (0.52) | KIF11EPAS1MAPTALDH1A1LMNA | |
| SCHEMBL11603516 | 0.78 | MAPT (0.41) | KIF11EPAS1MAPTALDH1A1KDM4E | |
| SCHEMBL11599131 | 0.75 | KIF11 (0.48) | KIF11EPAS1MAPTALDH1A1NPSR1 | |
| SCHEMBL11601120 | 0.74 | ALDH1A1 (0.48) | KIF11EPAS1MAPTALDH1A1KDM4E | |
| SCHEMBL11601195 | 0.74 | EPAS1 (0.52) | KIF11EPAS1MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4086364-A | AGRICULTURE | GAF CORPORATION (US) | 1978-04-25 | — | — | US | claimed |
| US-4086364-A | AGRICULTURE | GAF CORPORATION (US) | 1978-04-25 | — | — | US | disclosed |