Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 4/20 | 0.41 |
| ▸ | ADH1C | P00326 | 3/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | PHGDH | O43175 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 4/20 | 0.34 |
| ▸ | CTSL | P07711 | 2/20 | 0.34 |
| ▸ | CTSB | P07858 | 2/20 | 0.34 |
| ▸ | CTSH | P09668 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11047746 | 0.95 | — | — | |
| SCHEMBL11050854 | 0.86 | — | — | |
| SCHEMBL303775 | 0.74 | ADH1A (0.46) | ADH1AADH1CFAAHPHGDHMGLL | |
| SCHEMBL11832863 | 0.74 | PHGDH (0.41) | ADH1AADH1CFAAHPHGDHMGLL | |
| SCHEMBL5228372 | 0.74 | ADH1A (0.41) | ADH1AADH1CFAAHPHGDHMGLL | |
| SCHEMBL1678871 | 0.74 | ADH1A (0.46) | ADH1AADH1CFAAHPHGDHMGLL | |
| SCHEMBL1679240 | 0.74 | ADH1A (0.46) | ADH1AADH1CFAAHPHGDHMGLL | |
| SCHEMBL3055438 | 0.73 | NOS2 (0.39) | HRH3MEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL3448459 | 0.72 | ADH1A (0.35) | ADH1AADH1CFAAHPHGDHMGLL | |
| SCHEMBL11767385 | 0.72 | ADH1A (0.35) | ADH1AADH1CFAAHPHGDHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4196287-A | Process for the catalytic production of 2-substituted pyridines | LONZA LTD. (CH) | 1980-04-01 | — | — | US | claimed |
| EP-0029409-B1 | PROCESS FOR PREPARING 5-CYANO-5H-DIBENZ(B,F)AZEPINE AND 5H-DIBENZ(B,F)AZEPINE-5-CARBOXAMIDE | CIBA-GEIGY AG (CH) | 1984-08-15 | — | — | EP | disclosed |
| US-4436660-A | Process for the production of 5-cyano-and 5-carboxamido-5H-dibenz[b,f]azepines | CIBA-GEIGY CORPORATION (US) | 1984-03-13 | — | — | US | disclosed |
| EP-0029409-A1 | Process for preparing 5-cyano-5H-dibenz(b,f)azepine and 5H-dibenz(b,f)azepine-5-carboxamide | CIBA-GEIGY AG (CH) | 1981-05-27 | — | — | EP | disclosed |
| US-4196287-A | Process for the catalytic production of 2-substituted pyridines | LONZA LTD. (CH) | 1980-04-01 | — | — | US | disclosed |