SCHEMBL3448459

SCHEMBL3448459

N#CN(C1CCCCC1)C1CCCCC1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ADH1A P07327 7/20 0.35
ADH1C P00326 5/20 0.33
PHGDH O43175 2/20 0.32
MCOLN3 Q8TDD5 1/20 0.32
ADH4 P08319 1/20 0.31
ADH1B P00325 1/20 0.30
FDPS P14324 1/20 0.30
FAAH O00519 1/20 0.30
MGLL Q99685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11767385 1.00 ADH1A (0.35) ADH1AADH1CPHGDHMCOLN3ADH4
SCHEMBL11636935 0.78 LMNA (0.32)
SCHEMBL11082149 0.72 ADH1A (0.41) ADH1AADH1CPHGDHMCOLN3ADH1B
SCHEMBL303553 0.71 ADH1A (0.40) ADH1AADH1CPHGDHADH4ADH1B
SCHEMBL7538132 0.71 ADH1A (0.35) ADH1AADH1CPHGDHADH4ADH1B
SCHEMBL14855292 0.71 ADH1A (0.40) ADH1AADH1CPHGDHADH4ADH1B
SCHEMBL8745529 0.71 ADH1A (0.40) ADH1AADH1CPHGDHADH4ADH1B
SCHEMBL10012568 0.71 ADH1A (0.40) ADH1AADH1CPHGDHADH4ADH1B
SCHEMBL11824045 0.71 PHGDH (0.37) ADH1AADH1CPHGDHADH4ADH1B
SCHEMBL10013012 0.71 ADH1A (0.40) ADH1AADH1CPHGDHADH4ADH1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0245505-B2 TERMINAL-MODIFIED BLOCK COPOLYMER AND COMPOSITION CONTAINING SAID COPOLYMER ASAHI CHEMICAL IND (JP) 1996-08-14 EP claimed
US-5332784-A Conjugated diene, vinylaromatic copolymer ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1994-07-26 US claimed
US-4835209-A Rubber for tire treads and compositions thereof ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1989-05-30 US claimed
EP-0245505-A1 TERMINAL-MODIFIED BLOCK COPOLYMER AND COMPOSITION CONTAINING SAID COPOLYMER Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1987-11-19 EP claimed
US-4196287-A Process for the catalytic production of 2-substituted pyridines LONZA LTD. (CH) 1980-04-01 US claimed
US-11226345-B2 Antibodies to olanzapine haptens and use thereof JANSSEN PHARMACEUTICA NV (BE) 2022-01-18 US disclosed
US-11225527-B2 Antibodies to paliperidone haptens and use thereof JANSSEN PHARMACEUTICA NV (BE) 2022-01-18 US disclosed
US-20210017294-A9 ANTIBODIES TO QUETIAPINE HAPTENS AND USE THEREOF JANSSEN PHARMACEUTICA NV (BE) 2021-01-21 US disclosed
US-20200399400-A1 ANTIBODIES TO RISPERIDONE HAPTENS AND USE THEREOF JANSSEN PHARMACEUTICA NV (BE) 2020-12-24 US disclosed
US-10793644-B2 Antibodies to risperidone haptens and use thereof JANSSEN PHARMACEUTICA NV (BE) 2020-10-06 US disclosed
US-10712353-B2 Antibodies to olanzapine haptens and use thereof JANSSEN PHARMACEUTICA NV (BE) 2020-07-14 US disclosed
US-20200040107-A1 ANTIBODIES TO QUETIAPINE HAPTENS AND USE THEREOF JANSSEN PHARMACEUTICA NV (BE) 2020-02-06 US disclosed
US-4835209-A Rubber for tire treads and compositions thereof ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1989-05-30 US disclosed
EP-0252992-A1 Rubber-like polymers for tire treads, a process for their preparation, and compositions containing said polymers Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1988-01-20 EP disclosed
EP-0245505-A1 TERMINAL-MODIFIED BLOCK COPOLYMER AND COMPOSITION CONTAINING SAID COPOLYMER Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1987-11-19 EP disclosed
US-4529798-A Reacting the correcponding lithium, sodium, potassium or magnesium halide compound with a aminonitrile compound JOHN WYETH & BROTHER LIMITED (GB) 1985-07-16 US disclosed
EP-0054384-B1 PROCESS FOR PREPARING PYRIDINE DERIVATIVES JOHN WYETH & BROTHER LIMITED (GB) 1984-06-27 EP disclosed
EP-0054384-A1 Process for preparing pyridine derivatives JOHN WYETH & BROTHER LIMITED (GB) 1982-06-23 EP disclosed
US-4196287-A Process for the catalytic production of 2-substituted pyridines LONZA LTD. (CH) 1980-04-01 US disclosed
US-4098791-A Process for preparing 3-(cyanimino)-3-amino-propionitriles THE UPJOHN COMPANY (US) 1978-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10793644-B2 Antibodies to risperidone haptens and use thereof HTR4, HTR3C, OPRL1 ADH1A 1013/4885ADH1C 949/4885PHGDH 4471/4885
US-11225527-B2 Antibodies to paliperidone haptens and use thereof LY96, OPRL1, HTR3C ADH1A 408/4885ADH1C 387/4885PHGDH 3619/4885
US-11226345-B2 Antibodies to olanzapine haptens and use thereof HTR4, HTR3C, HTR1A ADH1A 550/4885ADH1C 564/4885PHGDH 4163/4885
US-10712353-B2 Antibodies to olanzapine haptens and use thereof HTR4, HTR3C, HTR1A ADH1A 550/4885ADH1C 564/4885PHGDH 4163/4885
US-20200399400-A1 ANTIBODIES TO RISPERIDONE HAPTENS AND USE THEREOF HTR4, HTR3C, OPRL1 ADH1A 1013/4885ADH1C 949/4885PHGDH 4471/4885
US-20200040107-A1 ANTIBODIES TO QUETIAPINE HAPTENS AND USE THEREOF HTR4, HTR3C, SLC6A4 ADH1A 912/4885ADH1C 995/4885PHGDH 3604/4885
US-20210017294-A9 ANTIBODIES TO QUETIAPINE HAPTENS AND USE THEREOF HTR4, HTR3C, SLC6A4 ADH1A 912/4885ADH1C 995/4885PHGDH 3604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.