Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11186310 | 0.87 | THRB (0.42) | L3MBTL1HTTATMTHRBALDH1A1 | |
| SCHEMBL11077043 | 0.87 | HTT (0.51) | L3MBTL1HTTATMTHRBALDH1A1 | |
| SCHEMBL11079986 | 0.85 | L3MBTL1 (0.54) | L3MBTL1HTTATMTHRBALDH1A1 | |
| SCHEMBL11074876 | 0.83 | THRB (0.58) | L3MBTL1HTTATMTHRBALDH1A1 | |
| SCHEMBL11077400 | 0.80 | L3MBTL1 (0.51) | L3MBTL1HTTATMTHRBALDH1A1 | |
| SCHEMBL11074781 | 0.80 | ALDH1A1 (0.53) | L3MBTL1HTTATMALDH1A1MAPK1 | |
| SCHEMBL11075114 | 0.80 | THRB (0.41) | L3MBTL1HTTATMTHRBALDH1A1 | |
| SCHEMBL11075441 | 0.79 | L3MBTL1 (0.52) | L3MBTL1HTTATMTHRBALDH1A1 | |
| SCHEMBL11076492 | 0.79 | HTT (0.52) | L3MBTL1HTTATMTHRBALDH1A1 | |
| SCHEMBL11081573 | 0.79 | L3MBTL1 (0.60) | L3MBTL1HTTATMTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0043858-B1 | HETERO RING-SUBSTITUTED OXOALKANOIC ACID DERIVATIVES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1984-04-18 | — | — | EP | claimed |
| US-4386092-A | IMMUNOMODULATORY | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1983-05-31 | — | — | US | claimed |
| EP-0043858-A1 | HETERO RING-SUBSTITUTED OXOALKANOIC ACID DERIVATIVES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1982-01-20 | — | — | EP | claimed |
| EP-0043858-B1 | HETERO RING-SUBSTITUTED OXOALKANOIC ACID DERIVATIVES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1984-04-18 | — | — | EP | disclosed |
| US-4386092-A | IMMUNOMODULATORY | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1983-05-31 | — | — | US | disclosed |
| EP-0043858-A1 | HETERO RING-SUBSTITUTED OXOALKANOIC ACID DERIVATIVES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1982-01-20 | — | — | EP | disclosed |