⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23113780 | 0.93 | FAAH (0.69) | — | |
| SCHEMBL6893226 | 0.91 | FAAH (0.67) | — | |
| SCHEMBL6256065 | 0.91 | FAAH (0.67) | — | |
| SCHEMBL11090505 | 0.91 | FAAH (0.67) | — | |
| SCHEMBL13163885 | 0.91 | FAAH (0.67) | — | |
| SCHEMBL11081119 | 0.91 | FAAH (0.67) | — | |
| SCHEMBL11084332 | 0.91 | FAAH (0.67) | — | |
| SCHEMBL11252256 | 0.85 | FAAH (0.53) | — | |
| SCHEMBL6264472 | 0.83 | FAAH (0.52) | — | |
| SCHEMBL6897603 | 0.83 | FAAH (0.82) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3963071-A1 | COMPOSITIONS AND METHODS FOR GENERATING DIVERSITY AT TARGETED NUCLEIC ACID SEQUENCES | Monsanto Technology LLC (US) | 2022-03-09 | — | — | EP | claimed |
| CN-113906137-A | Compositions and methods for generating diversity at a targeted nucleic acid sequence | 孟山都技术公司 | 2022-01-07 | — | — | CN | claimed |
| WO-2020223642-A9 | COMPOSITIONS AND METHODS FOR GENERATING DIVERSITY AT TARGETED NUCLEIC ACID SEQUENCES | MONSANTO TECHNOLOGY LLC (US) | 2021-09-30 | — | — | WO | claimed |
| US-20200347389-A1 | COMPOSITIONS AND METHODS FOR GENERATING DIVERSITY AT TARGETED NUCLEIC ACID SEQUENCES | MONSANTO TECHNOLOGY LLC (US) | 2020-11-05 | — | — | US | claimed |
| WO-2020223642-A1 | COMPOSITIONS AND METHODS FOR GENERATING DIVERSITY AT TARGETED NUCLEIC ACID SEQUENCES | MONSANTO TECHNOLOGY LLC (US) | 2020-11-05 | — | — | WO | claimed |
| EP-4263820-A1 | ENGINEERED SSDNASE-FREE CRISPR ENDONUCLEASES | Monsanto Technology LLC (US) | 2023-10-25 | — | — | EP | disclosed |
| WO-2022132996-A1 | ENGINEERED SSDNASE-FREE CRISPR ENDONUCLEASES | MONSANTO TECHNOLOGY LLC (US) | 2022-06-23 | — | — | WO | disclosed |
| US-20220195405-A1 | ENGINEERED SSDNASE-FREE CRISPR ENDONUCLEASES | MONSANTO TECHNOLOGY LLC (US) | 2022-06-23 | — | — | US | disclosed |
| EP-3963071-A1 | COMPOSITIONS AND METHODS FOR GENERATING DIVERSITY AT TARGETED NUCLEIC ACID SEQUENCES | Monsanto Technology LLC (US) | 2022-03-09 | — | — | EP | disclosed |
| CN-113906137-A | Compositions and methods for generating diversity at a targeted nucleic acid sequence | 孟山都技术公司 | 2022-01-07 | — | — | CN | disclosed |
| WO-2020223642-A9 | COMPOSITIONS AND METHODS FOR GENERATING DIVERSITY AT TARGETED NUCLEIC ACID SEQUENCES | MONSANTO TECHNOLOGY LLC (US) | 2021-09-30 | — | — | WO | disclosed |
| CN-108273478-B | Formaldehyde removal composition and product | 李怀玉 | 2021-03-02 | — | — | CN | disclosed |
| US-20200347389-A1 | COMPOSITIONS AND METHODS FOR GENERATING DIVERSITY AT TARGETED NUCLEIC ACID SEQUENCES | MONSANTO TECHNOLOGY LLC (US) | 2020-11-05 | — | — | US | disclosed |
| WO-2020223642-A1 | COMPOSITIONS AND METHODS FOR GENERATING DIVERSITY AT TARGETED NUCLEIC ACID SEQUENCES | MONSANTO TECHNOLOGY LLC (US) | 2020-11-05 | — | — | WO | disclosed |
| US-4489091-A | ESTERASE AND ANTIBODY INHIBITORS | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1984-12-18 | — | — | US | disclosed |
| US-4411911-A | Method of treating hyperlipidemia and inflammation with sulfonate derivatives | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1983-10-25 | — | — | US | disclosed |