Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.34 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.34 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.34 |
| ▸ | PARP12 | Q9H0J9 | 1/20 | 0.34 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.34 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.34 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11077508 | 0.80 | LIMK1 (0.49) | PIM1PIM2EGFRHRH4MAPT | |
| SCHEMBL16785723 | 0.70 | PIM1 (0.42) | PIM1PIM2MAPTRAB9AIDO1 | |
| SCHEMBL15497381 | 0.67 | PIM1 (0.40) | PIM1PIM2EGFRMAPTRAB9A | |
| SCHEMBL753610 | 0.67 | PIM1 (0.40) | PIM1PIM2EGFRMAPTRAB9A | |
| SCHEMBL27058862 | 0.67 | PIM1 (0.48) | PIM1PIM2EGFRHRH4MAPT | |
| SCHEMBL11128266 | 0.67 | HRH4 (0.39) | PIM1PIM2HRH4MAPTTP53 | |
| SCHEMBL11146665 | 0.67 | MAPT (0.38) | HRH4MAPTRAB9APARP15PARP10 | |
| SCHEMBL1609993 | 0.66 | CYP2A6 (0.42) | PIM1PIM2MAPTRAB9AIDO1 | |
| SCHEMBL23280687 | 0.65 | TDP1 (0.40) | PIM1PIM2EGFRMAPTRAB9A | |
| SCHEMBL24778844 | 0.65 | PIM1 (0.46) | PIM1PIM2EGFRHRH4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4431657-A | Analgesic compositions consisting of 2H-benzothieno[3,2-c]pyrazol-3-amine derivatives | AYERST, MCKENNA & HARRISON INC. (CA) | 1984-02-14 | — | — | US | disclosed |