Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.37 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.37 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.37 |
| ▸ | PARP12 | Q9H0J9 | 1/20 | 0.37 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.37 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.37 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11149355 | 0.80 | LIMK1 (0.45) | MAPTRAB9AHRH4KDM4EALDH1A1 | |
| SCHEMBL11146925 | 0.77 | GPR35 (0.34) | LIMK1 | |
| SCHEMBL11144383 | 0.75 | KDR (0.37) | MAPTPARP10PARP2PARP15PARP14 | |
| SCHEMBL11145581 | 0.74 | MEN1 (0.52) | MAPTRAB9ABCL2L1MCL1KDM4E | |
| SCHEMBL12412980 | 0.72 | MCL1 (0.38) | MAPTRAB9APARP10PARP2PARP15 | |
| SCHEMBL12412960 | 0.72 | MCL1 (0.38) | MAPTRAB9APARP10PARP2PARP15 | |
| SCHEMBL12413187 | 0.71 | MCL1 (0.37) | MAPTRAB9APARP10PARP2PARP15 | |
| SCHEMBL3123994 | 0.70 | BCL2L1 (0.47) | MAPTRAB9APARP10PARP2PARP15 | |
| SCHEMBL17281047 | 0.70 | MCL1 (0.36) | MAPTRAB9APARP10PARP2PARP15 | |
| SCHEMBL11156297 | 0.70 | PRMT5 (0.36) | GAALMNACYP2A6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005357-B1 | N-(BENZOTHIENOPYRAZOL)-AMIDES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-02-09 | — | — | EP | disclosed |
| EP-0005357-A1 | N-(Benzothienopyrazol)-amides and pharmaceutical compositions containing them | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-11-14 | — | — | EP | disclosed |
| US-4140785-A | N-(benzothienopyrazol)amide antirhinoviral agents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-02-20 | — | — | US | disclosed |