Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | BHMT | Q93088 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13227791 | 0.92 | TSHR (0.48) | ALDH1A1TSHRPLA2G4BLMNAHSD17B10 | |
| SCHEMBL26777323 | 0.89 | TSHR (0.50) | ALDH1A1TSHRPLA2G4BLMNAKMT2A | |
| SCHEMBL11639760 | 0.83 | CES2 (0.50) | TSHRPLA2G4BHSD17B10CA12CA14 | |
| SCHEMBL11639935 | 0.83 | CES2 (0.50) | TSHRPLA2G4BHSD17B10CA12CA14 | |
| SCHEMBL7161132 | 0.83 | CES2 (0.50) | TSHRPLA2G4BHSD17B10CA12CA14 | |
| SCHEMBL10503461 | 0.83 | CES2 (0.50) | TSHRPLA2G4BHSD17B10CA12CA14 | |
| SCHEMBL8895243 | 0.83 | CES2 (0.50) | TSHRPLA2G4BHSD17B10CA12CA14 | |
| SCHEMBL10608277 | 0.83 | TSHR (0.46) | ALDH1A1TSHRLMNAHSD17B10MEN1 | |
| SCHEMBL9261267 | 0.83 | ALDH1A1 (0.64) | ALDH1A1TSHRPLA2G4BLMNAHSD17B10 | |
| SCHEMBL10502771 | 0.83 | CES2 (0.50) | TSHRPLA2G4BHSD17B10CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4444766-A | ANTITUMOR | BOEHRINGER MANNHEIM GMBH (DE) | 1984-04-24 | — | — | US | disclosed |