SCHEMBL13227791

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11082919	0.92	ALDH1A1 (0.47)	TSHRALDH1A1HSD17B10PLA2G4BKMT2A
	SCHEMBL26777323	0.89	TSHR (0.50)	TSHRALDH1A1PLA2G4BKMT2ALMNA
	SCHEMBL112204	0.85	TSHR (0.63)	TSHRALDH1A1HSD17B10KMT2AMEN1
	SCHEMBL15282755	0.83	TSHR (0.60)	TSHRALDH1A1HSD17B10KMT2AMEN1
	SCHEMBL15631195	0.82	TSHR (0.50)	TSHRALDH1A1HSD17B10PLA2G4BKMT2A
	SCHEMBL12421758	0.82	ALDH1A1 (0.42)	TSHRALDH1A1HSD17B10PLA2G4BKMT2A
	SCHEMBL12417193	0.81	LMNA (0.50)	TSHRALDH1A1PLA2G4BKMT2AMEN1
	SCHEMBL14353413	0.81	TSHR (0.67)	TSHRALDH1A1HSD17B10KMT2AMEN1
	SCHEMBL23135308	0.80	ALDH1A1 (0.41)	TSHRALDH1A1HSD17B10PLA2G4BKMT2A
	SCHEMBL11345104	0.80	TSHR (0.48)	TSHRALDH1A1HSD17B10KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.