SCHEMBL1108308

SCHEMBL1108308

O=C1CCC(=O)N1CCNCCN1C(=O)CCC1=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
HTT P42858 2/20 0.40
OGA O60502 1/20 0.38
HEXA P06865 1/20 0.38
HEXB P07686 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
HPGD P15428 1/20 0.38
POLB P06746 2/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA4 P22748 1/20 0.36
CA9 Q16790 1/20 0.36
FAAH O00519 1/20 0.36
MGLL Q99685 1/20 0.36
SIRT1 Q96EB6 2/20 0.35
CHRM2 P08172 1/20 0.34
CHRM4 P08173 1/20 0.34
CHRM5 P08912 1/20 0.34
CHRM1 P11229 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11875056 0.89 ACE2 (0.48) MEN1KMT2AHTTOGAHEXA
SCHEMBL9998986 0.87 ACE2 (0.47) MEN1KMT2AHTTOGAHEXA
SCHEMBL24160856 0.87 FAAH (0.41) MEN1KMT2AHTTOGAHEXA
SCHEMBL28480225 0.82 MGLL (0.49) HTTSMN1; SMN2HPGDFAAHMGLL
SCHEMBL14024976 0.82 MEN1 (0.36) MEN1KMT2AHTTOGAHEXA
SCHEMBL24235571 0.80 KMT2A (0.42) MEN1KMT2AHTTSMN1; SMN2HPGD
SCHEMBL8863095 0.80 POLB (0.43) MEN1KMT2AHTTSMN1; SMN2HPGD
SCHEMBL28542650 0.78 KMT2A (0.41) MEN1KMT2AHTTSMN1; SMN2HPGD
SCHEMBL14269651 0.76 FAAH (0.34) MEN1KMT2AHTTSMN1; SMN2HPGD
Hydrochloric Acid SCHEMBL5755220 0.75 DPP7 (0.54) MEN1KMT2ASMN1; SMN2POLBCHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180051228-A1 LUBRICATING OIL COMPOSITION FOR FOUR STROKE ENGINE IDEMITSU KOSAN CO., LTD. (JP) 2018-02-22 US disclosed
US-9850446-B2 Lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2017-12-26 US disclosed
US-9759323-B2 Sliding member and method for producing same NISSAN MOTOR CO., LTD. (JP) 2017-09-12 US disclosed
US-20160115419-A1 LUBRICANT COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2016-04-28 US disclosed
US-20150362072-A1 SLIDING MEMBER AND METHOD FOR PRODUCING SAME NISSAN MOTOR CO., LTD. (JP) 2015-12-17 US disclosed
US-8575076-B2 Sliding member and production process thereof NISSAN MOTOR CO., LTD. (JP) 2013-11-05 US disclosed
US-8530051-B2 High strength gear, power transmission mechanism using same, and production method for high strength gear NISSAN MOTOR CO., LTD. (JP) 2013-09-10 US disclosed
US-20120172266-A1 LUBRICANT COMPOSITION NIPPON ITF INC. (JP) 2012-07-05 US disclosed
US-8206035-B2 Low-friction sliding mechanism, low-friction agent composition and method of friction reduction NISSAN MOTOR CO., LTD. (JP) 2012-06-26 US disclosed
US-8152377-B2 Low-friction sliding mechanism NISSAN MOTOR CO., LTD. (JP) 2012-04-10 US disclosed
US-20110028361-A1 LOW-FRICTION SLIDING MECHANISM NISSAN MOTOR CO., LTD. 2011-02-03 US disclosed
US-7771821-B2 Low-friction sliding member and low-friction sliding mechanism using same NISSAN MOTOR CO., LTD. (JP) 2010-08-10 US disclosed
US-7650976-B2 Low-friction sliding member in transmission, and transmission oil therefor NISSAN MOTOR CO., LTD. (JP) 2010-01-26 US disclosed
US-20090054277-A1 SLIDING MEMBER AND PRODUCTION PROCESS THEREOF NISSAN MOTOR CO., LTD. 2009-02-26 US disclosed
US-20080236984-A1 LOW-FRICTION SLIDING MEMBER IN TRANSMISSION, AND TRANSMISSION OIL THEREFOR NISSAN MOTOR CO., LTD. 2008-10-02 US disclosed
US-7322749-B2 Low-friction sliding mechanism NISSAN MOTOR CO., LTD. (JP) 2008-01-29 US disclosed
WO-1994023758-A1 RADIOLABELED COMPOUNDS FOR THROMBUS IMAGING DIATECH, INC. (US) 1994-10-27 WO disclosed