SCHEMBL14024976

SCHEMBL14024976

O=C1CCC(=O)C1CCNCCN1C(=O)CCC1=O

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
HTT P42858 2/20 0.35
HPGD P15428 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
OGA O60502 1/20 0.30
HEXA P06865 1/20 0.30
HEXB P07686 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1108308 0.82 MEN1 (0.44) MEN1KMT2AHTTHPGDSMN1; SMN2
SCHEMBL12912967 0.81 MEN1 (0.33) MEN1KMT2AHTT
SCHEMBL11875056 0.73 ACE2 (0.48) MEN1KMT2AHTTHPGDSMN1; SMN2
SCHEMBL24160856 0.72 FAAH (0.41) MEN1KMT2AHTTHPGDSMN1; SMN2
SCHEMBL9998986 0.72 ACE2 (0.47) MEN1KMT2AHTTHPGDSMN1; SMN2
SCHEMBL28480225 0.68 MGLL (0.49) HTTHPGDSMN1; SMN2
SCHEMBL24235571 0.66 KMT2A (0.42) MEN1KMT2AHTTHPGDSMN1; SMN2
SCHEMBL8863095 0.66 POLB (0.43) MEN1KMT2AHTTHPGDSMN1; SMN2
SCHEMBL28542650 0.65 KMT2A (0.41) MEN1KMT2AHTTHPGDSMN1; SMN2
SCHEMBL14269651 0.62 FAAH (0.34) MEN1KMT2AHTTHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080248981-A1 Lubricating base oil, an ashless friction modifier and a phosphorus-containing anti-wear agent; increasing the isomerization rate from normal paraffins to isoparaffins, improving the low temperature viscosity property by lowering the viscosity of the lubricating base oil NIPPON OIL CORPORATION 2008-10-09 US disclosed