Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INMT | O95050 | 5/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL11150960 | 0.76 | BRD4 (0.35) | CA5ACA5B | |
| SCHEMBL25337137 | 0.69 | INMT (0.30) | INMT | |
| Sulfuric Acid SCHEMBL8471322 | 0.67 | CYP1A2 (0.48) | CA5ACA5B | |
| N-Methyl Pyrrolidine (Nmp) SCHEMBL21616460 | 0.63 | CA5A (0.38) | CA5ACA5B | |
| N-Methylpiperidine SCHEMBL21616470 | 0.61 | CA1 (0.39) | CA5ACA5B | |
| Sulfuric Acid SCHEMBL669805 | 0.61 | CA5A (0.86) | CA5ACA5B | |
| Sulfuric Acid SCHEMBL15899693 | 0.61 | CA5A (0.86) | CA5ACA5B | |
| Sulfuric Acid SCHEMBL410140 | 0.61 | CA5A (0.86) | CA5ACA5B | |
| Sulfuric Acid SCHEMBL5672134 | 0.61 | CA5A (0.86) | CA5ACA5B | |
| Sulfuric Acid SCHEMBL19689578 | 0.61 | CA5A (0.86) | CA5ACA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009362-B1 | HETEROCYCLIC DERIVATIVES OF GUANIDINE, THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS COMPRISING THEM | McNeilab, Inc. (US) | 1984-06-27 | — | — | EP | disclosed |
| EP-0009362-A1 | Heterocyclic derivatives of guanidine, their preparation and pharmaceutical formulations comprising them | McNeilab, Inc. (US) | 1980-04-02 | — | — | EP | disclosed |
| US-4182865-A | HYPOGLYCEMIC AGENTS | MCNEIL LABORATORIES, INC. (US) | 1980-01-08 | — | — | US | disclosed |