Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11086808 | 0.73 | GLA (0.47) | BCHEACHESIGMAR1HRH3GAA | |
| SCHEMBL11849978 | 0.73 | BCHE (0.40) | BCHEACHESIGMAR1HRH3 | |
| Hydrochloric Acid SCHEMBL11082477 | 0.72 | GLA (0.46) | BCHEACHESIGMAR1HRH3GAA | |
| SCHEMBL9756628 | 0.70 | BCHE (0.41) | BCHEACHESIGMAR1HRH3 | |
| SCHEMBL11502411 | 0.70 | BCHE (0.56) | BCHEACHESIGMAR1 | |
| SCHEMBL11769008 | 0.69 | HRH3 (0.46) | BCHEACHESIGMAR1HRH3GAA | |
| SCHEMBL11760710 | 0.69 | HRH3 (0.46) | BCHEACHESIGMAR1HRH3GAA | |
| SCHEMBL11768994 | 0.69 | HRH3 (0.46) | BCHEACHESIGMAR1HRH3GAA | |
| SCHEMBL11760720 | 0.69 | HRH3 (0.46) | BCHEACHESIGMAR1HRH3GAA | |
| SCHEMBL11760698 | 0.69 | HRH3 (0.46) | BCHEACHESIGMAR1HRH3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0028717-B1 | 6,7-BENZOMORPHAN DERIVATIVES, PROCESSES FOR THEIR PRODUCTION, PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | ACF CHEMIEFARMA NV (NL) | 1984-08-15 | — | — | EP | disclosed |
| US-4425353-A | Analgesic 5-oxygenated-6,7-benzomorphan derivatives | ACF CHEMIEFARMA NV (NL) | 1984-01-10 | — | — | US | disclosed |
| US-4406904-A | Method of inhibiting luteinizing hormone secretion with 6,7-benzomorphan derivatives | ACF CHEMIEFARMA NV (NL) | 1983-09-27 | — | — | US | disclosed |
| EP-0028717-A1 | 6,7-Benzomorphan derivatives, processes for their production, pharmaceutical compositions containing said derivatives and their use as pharmaceuticals | ACF CHEMIEFARMA NV (NL) | 1981-05-20 | — | — | EP | disclosed |