Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9441400 | 0.82 | BCHE (0.40) | BCHEACHEHRH3SIGMAR1 | |
| SCHEMBL11084149 | 0.70 | BCHE (0.44) | BCHEACHEHRH3SIGMAR1 | |
| SCHEMBL2066096 | 0.69 | OPRK1 (0.43) | HRH3SIGMAR1 | |
| SCHEMBL11760720 | 0.69 | HRH3 (0.46) | BCHEACHEHRH3SIGMAR1 | |
| SCHEMBL11768994 | 0.69 | HRH3 (0.46) | BCHEACHEHRH3SIGMAR1 | |
| SCHEMBL11769008 | 0.69 | HRH3 (0.46) | BCHEACHEHRH3SIGMAR1 | |
| SCHEMBL11760698 | 0.69 | HRH3 (0.46) | BCHEACHEHRH3SIGMAR1 | |
| SCHEMBL11760710 | 0.69 | HRH3 (0.46) | BCHEACHEHRH3SIGMAR1 | |
| SCHEMBL2066095 | 0.69 | BCHE (0.44) | BCHEACHEHRH3SIGMAR1 | |
| SCHEMBL11766646 | 0.68 | HRH3 (0.45) | BCHEACHEHRH3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0283848-B1 | PROCESS FOR THE PREPARATION OF ISOQUINOLINES | F. HOFFMANN-LA ROCHE AG (CH) | 1991-05-15 | — | — | EP | disclosed |
| EP-0283848-A1 | Process for the preparation of isoquinolines | F. HOFFMANN-LA ROCHE AG (CH) | 1988-09-28 | — | — | EP | disclosed |