Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11760710 | 1.00 | HRH3 (0.46) | HRH3SPHK2GAAHPGDBCHE | |
| SCHEMBL11768994 | 1.00 | HRH3 (0.46) | HRH3SPHK2GAAHPGDBCHE | |
| SCHEMBL11769008 | 1.00 | HRH3 (0.46) | HRH3SPHK2GAAHPGDBCHE | |
| SCHEMBL11760698 | 1.00 | HRH3 (0.46) | HRH3SPHK2GAAHPGDBCHE | |
| SCHEMBL11763716 | 0.80 | HRH3 (0.45) | HRH3GAAHPGDBCHEACHE | |
| SCHEMBL11763720 | 0.80 | HRH3 (0.45) | HRH3GAAHPGDBCHEACHE | |
| SCHEMBL11766646 | 0.80 | HRH3 (0.45) | HRH3GAAHPGDBCHEACHE | |
| SCHEMBL27078273 | 0.80 | SPHK2 (0.56) | HRH3SPHK2SIGMAR1 | |
| SCHEMBL11477757 | 0.78 | FPR1 (0.48) | HRH3SPHK2GAA | |
| SCHEMBL11385289 | 0.77 | HTR1A (0.55) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4022792-A | ANALGESICS | STERLING DRUG INC. (US) | 1977-05-10 | — | — | US | disclosed |
| US-3976653-A | ANALGESIC ANTAGONIST | STERLING DRUG INC. (US) | 1976-08-24 | — | — | US | disclosed |