Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11075195 | 0.88 | KMT2A (0.39) | MEN1KMT2AMAPK1PIK3CAMAPK8 | |
| SCHEMBL11082728 | 0.87 | MEN1 (0.36) | MEN1KMT2AMAPK1PIK3CAMAPK8 | |
| SCHEMBL11084575 | 0.85 | MEN1 (0.34) | MEN1KMT2AMAPK1PIK3CAMAPK8 | |
| SCHEMBL10940185 | 0.77 | HTT (0.39) | MEN1KMT2AALDH1A1CYP3A4HRH4 | |
| SCHEMBL11077460 | 0.77 | MAPK1 (0.35) | MEN1KMT2AMAPK1PIK3CAMAPK8 | |
| SCHEMBL10941009 | 0.77 | MEN1 (0.39) | MEN1KMT2ATDP1ALDH1A1CYP3A4 | |
| SCHEMBL11076390 | 0.76 | MAPT (0.43) | MEN1KMT2AALDH1A1CYP3A4KDM4E | |
| SCHEMBL10943146 | 0.75 | MEN1 (0.39) | MEN1KMT2ATDP1ALDH1A1CYP3A4 | |
| SCHEMBL10939016 | 0.75 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1CYP3A4HRH4 | |
| SCHEMBL11081532 | 0.75 | NPC1 (0.32) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4462994-A | O-ARYLPHOSPHATE DERIVATIVE OF QUINOXALINE | NISSAN CHEMICAL INDUSTRIES, INC. (JP) | 1984-07-31 | — | — | US | claimed |