Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.43 |
| ▸ | NPC1 | O15118 | 9/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | STAT1 | P42224 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11078682 | 0.89 | NPC1 (0.35) | MAPTNPC1KDM4ERAB9AALDH1A1 | |
| SCHEMBL11075195 | 0.89 | KMT2A (0.39) | MAPTNPC1KDM4ERAB9AALDH1A1 | |
| SCHEMBL11077460 | 0.89 | MAPK1 (0.35) | MAPTNPC1KDM4ERAB9AALDH1A1 | |
| SCHEMBL11077871 | 0.87 | TDO2 (0.34) | NPC1RAB9A | |
| SCHEMBL11084393 | 0.76 | MEN1 (0.39) | KDM4EALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL11082728 | 0.73 | MEN1 (0.36) | MAPTKMT2AMEN1TP53 | |
| SCHEMBL3004664 | 0.73 | NPC1 (0.58) | MAPTNPC1KDM4ERAB9AALDH1A1 | |
| Demeton S SCHEMBL6047076 | 0.72 | NPC1 (0.49) | MAPTNPC1KDM4ERAB9AALDH1A1 | |
| SCHEMBL11081532 | 0.72 | NPC1 (0.32) | NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL10624057 | 0.72 | MEN1 (0.38) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4462994-A | O-ARYLPHOSPHATE DERIVATIVE OF QUINOXALINE | NISSAN CHEMICAL INDUSTRIES, INC. (JP) | 1984-07-31 | — | — | US | claimed |
| EP-0065287-A2 | N-containing heterocyclic ring-substituted O-arylphosphate derivatives, preparation thereof, and insecticides containing said derivatives | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1982-11-24 | — | — | EP | claimed |
| US-4462994-A | O-ARYLPHOSPHATE DERIVATIVE OF QUINOXALINE | NISSAN CHEMICAL INDUSTRIES, INC. (JP) | 1984-07-31 | — | — | US | disclosed |
| EP-0065287-A2 | N-containing heterocyclic ring-substituted O-arylphosphate derivatives, preparation thereof, and insecticides containing said derivatives | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1982-11-24 | — | — | EP | disclosed |