Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NMT2 | O60551 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11075195 | 0.89 | KMT2A (0.39) | MAPK1PIK3CAMAPK8MAPK9MAPK10 | |
| SCHEMBL11076390 | 0.89 | MAPT (0.43) | MAPTALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL11077871 | 0.89 | TDO2 (0.34) | MAPK1PIK3CAMAPK8MAPK9MAPK10 | |
| SCHEMBL11078682 | 0.86 | NPC1 (0.35) | MAPK1PIK3CAMAPK8MAPK9MAPK10 | |
| SCHEMBL11084393 | 0.77 | MEN1 (0.39) | MAPK1PIK3CAMAPK8MAPK9MAPK10 | |
| SCHEMBL10947095 | 0.75 | HTT (0.43) | MAPTALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL11082728 | 0.74 | MEN1 (0.36) | MAPK1PIK3CAMAPK8MAPK9MAPK10 | |
| SCHEMBL11084575 | 0.71 | MEN1 (0.34) | MAPK1PIK3CAMAPK8MAPK9MAPK10 | |
| SCHEMBL10358876 | 0.71 | PKM (0.39) | MAPTKMT2AMEN1 | |
| SCHEMBL11282447 | 0.70 | KDM4E (0.47) | MAPK1MAPTALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4462994-A | O-ARYLPHOSPHATE DERIVATIVE OF QUINOXALINE | NISSAN CHEMICAL INDUSTRIES, INC. (JP) | 1984-07-31 | — | — | US | claimed |
| US-4462994-A | O-ARYLPHOSPHATE DERIVATIVE OF QUINOXALINE | NISSAN CHEMICAL INDUSTRIES, INC. (JP) | 1984-07-31 | — | — | US | disclosed |
| EP-0065287-A2 | N-containing heterocyclic ring-substituted O-arylphosphate derivatives, preparation thereof, and insecticides containing said derivatives | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1982-11-24 | — | — | EP | disclosed |