Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11086889 | 0.92 | SSTR3 (0.37) | MEN1KMT2ACYP2D6HTR7CYP3A4 | |
| SCHEMBL11085886 | 0.92 | PDE5A (0.36) | HTR2CMEN1KMT2ACYP2D6HTR7 | |
| SCHEMBL11081951 | 0.92 | ESR1 (0.40) | MEN1KMT2ACHRNA7ALDH1A1SSTR3 | |
| SCHEMBL11089610 | 0.90 | ADRA1A (0.41) | MEN1KMT2AHTR7KDM4ETSHR | |
| SCHEMBL11093337 | 0.90 | HTR7 (0.43) | HTR6MEN1KMT2ACYP2D6HTR7 | |
| SCHEMBL11082615 | 0.89 | HTR2C (0.37) | HTR2CMEN1KMT2A | |
| SCHEMBL11092628 | 0.89 | DRD2 (0.41) | MEN1KMT2AHTR7KDM4ETSHR | |
| SCHEMBL11083470 | 0.89 | SSTR3 (0.39) | HTR2AHTR2CMEN1KMT2AKDM4E | |
| SCHEMBL11084625 | 0.89 | RB1 (0.38) | HTR2AHTR2CHTR6MEN1KMT2A | |
| SCHEMBL11082610 | 0.88 | HTR7 (0.45) | KMT2AHTR7MAPKAPK2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115607-A1 | Tetrahydrocarbazol derivatives | MERCK PATENT GmbH (DE) | 1984-08-15 | — | — | EP | claimed |
| EP-0115607-A1 | Tetrahydrocarbazol derivatives | MERCK PATENT GmbH (DE) | 1984-08-15 | — | — | EP | disclosed |