SCHEMBL110854

SCHEMBL110854

COc1ccc(Cl)c(N)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.57
MEN1 O00255 2/20 0.57
MAPT P10636 2/20 0.57
THRB P10828 2/20 0.57
KMT2A Q03164 2/20 0.57
TDP1 Q9NUW8 3/20 0.55
GAA P10253 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
KDM4E B2RXH2 1/20 0.55
RECQL P46063 1/20 0.55
BLM P54132 1/20 0.55
MCL1 Q07820 1/20 0.55
CYP3A4 P08684 3/20 0.52
TP53 P04637 1/20 0.50
TSHR P16473 1/20 0.50
HSP90AA1 P07900 2/20 0.49
HSP90AB1 P08238 2/20 0.49
NPC1 O15118 1/20 0.48
CA12 O43570 3/20 0.46
CA1 P00915 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL414955 0.98 ALDH1A1 (0.61) ALDH1A1MEN1MAPTTHRBKMT2A
Hydrochloric Acid SCHEMBL20641579 0.96 ALDH1A1 (0.53) ALDH1A1MEN1MAPTTHRBKMT2A
SCHEMBL6585548 0.86 ALDH1A1 (0.47) ALDH1A1MEN1MAPTTHRBKMT2A
SCHEMBL922966 0.82 ALDH1A1 (0.57) ALDH1A1MEN1MAPTTHRBKMT2A
SCHEMBL13577131 0.80 MAOB (0.54) ALDH1A1MAPTTDP1SMN1; SMN2NPC1
Hydrochloric Acid SCHEMBL6235407 0.80 ALDH1A1 (0.61) ALDH1A1MEN1MAPTTHRBKMT2A
SCHEMBL8599820 0.79 MAOB (0.62) MEN1KMT2ANPC1
SCHEMBL4083971 0.79 MAOB (0.51) ALDH1A1KMT2AKDM4ECYP3A4
SCHEMBL13577145 0.79 ALDH1A1 (0.41) ALDH1A1MEN1MAPTTHRBKMT2A
SCHEMBL8603974 0.79 ENPP2 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 630 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116514669-B Synthesis method of 2-chloro-5-phenoxyaniline 上海灵瑞医药有限公司 2025-02-28 CN claimed
CN-114031545-A Synthetic method of 2-methoxy-6-phenylcarbazole 河南省科学院化学研究所有限公司 2022-02-11 CN claimed
US-20200131431-A1 CHEMICAL ADDITIVES AND SURFACTANT COMBINATIONS FOR FAVORABLE WETTABILITY ALTERATION AND IMPROVED HYDROCARBON RECOVERY FACTORS ALCHEMY SCIENCES INC (US) 2020-04-30 US claimed
EP-1773768-B1 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS EXELIXIS INC (US) 2018-08-22 EP claimed
CN-102993023-A Preparation method of mono-substituted para-chloroaniline UNIV SHANGHAI ENG SCIENCE 2013-03-27 CN claimed
EP-1451160-B1 PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN ICAGEN INC (US) 2010-01-13 EP claimed
EP-1773768-A4 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS EXELIXIS INC (US) 2008-08-06 EP claimed
EP-1773768-A2 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS Exelixis, Inc. (US) 2007-04-18 EP claimed
WO-2006012642-A2 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS EXELIXIS, INC. (US) 2006-02-02 WO claimed
EP-4615838-A1 SUBSTITUTED BI-AND TRICYCLIC HSET INHIBITORS Merck Patent GmbH (DE) 2025-09-17 EP disclosed
US-20250282736-A1 SMALL MOLECULE MODULATORS OF HUMAN PREGNANE X RECEPTOR ST JUDE CHILDRENS RES HOSPITAL (US) 2025-09-11 US disclosed
US-12378242-B2 Inhibiting CREB binding protein (CBP) FORMA THERAPEUTICS, INC. (US) 2025-08-05 US disclosed
EP-4587433-A1 3-(1H-INDOLE-2-CARBONYL)-6,6-DIMETHYL-N-((S)-1-OXO-3-((S)-2-OXOPYRROLIDIN-3-YL)P ROPAN-2-YL)-3-AZABICYCLO[3.1.0]HEXANE-2-CARBOXAMIDE DERIVATIVES AS MPRO INHIBITORS FOR THE TREATMENT OF CORONAVIRUS INFECTIONS Takeda Pharmaceutical Company Limited (JP) 2025-07-23 EP disclosed
WO-2025119975-A1 A METHOD FOR SYNTHESIS OF HARMINE RECONNECT LABS AG (CH) 2025-06-12 WO disclosed
US-4118232-A Photographic material containing sulphonic acid group containing disazo dyestuffs CIBA-GEIGY AG (CH) 1978-10-03 US disclosed
US-4079052-A Diazopigments containing pyridine derivatives CIBA-GEIGY CORPORATION (US) 1978-03-14 US disclosed
US-4056522-A PIGMENTS HOECHST AKTIENGESELLSCHAFT (DT) 1977-11-01 US disclosed
US-4051123-A Sulfonic-acid-group containing disazo dyestuffs CIBA-GEIGY AG (CH) 1977-09-27 US disclosed
US-4024272-A Tetracyclic compounds MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-05-17 US disclosed
US-3984405-A PYRIDO(3,2-B)(1,4)OXAZIN-3(4H)-ONES E. R. SQUIBB & SONS, INC. (US) 1976-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12378242-B2 Inhibiting CREB binding protein (CBP) CREBBP, EP300, CREB1 ALDH1A1 3592/4885MEN1 3661/4885MAPT 1879/4885
US-20250282736-A1 SMALL MOLECULE MODULATORS OF HUMAN PREGNANE X RECEPTOR NR1H4, NR1I2, NR1I3 ALDH1A1 3469/4885MEN1 4207/4885MAPT 3783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.