Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11694122 | 0.87 | LMNA (0.46) | LMNAMAPTHTTALDH1A1TDP1 | |
| SCHEMBL8901567 | 0.86 | PKM (0.51) | LMNAPDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL9247558 | 0.84 | LMNA (0.53) | LMNAMAPTHTTALDH1A1TDP1 | |
| SCHEMBL30837492 | 0.84 | PDGFRB (0.55) | LMNAPDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL12108924 | 0.84 | PDGFRB (0.55) | LMNAPDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL28892668 | 0.83 | LMNA (0.43) | LMNAMAPTGAAHTTALDH1A1 | |
| SCHEMBL11404100 | 0.82 | TSHR (0.50) | PDGFRBFGFR1PDGFRAFLT1FGFR3 | |
| SCHEMBL12937577 | 0.81 | LMNA (0.50) | LMNAMAPTHTTALDH1A1TDP1 | |
| SCHEMBL11721435 | 0.81 | LMNA (0.53) | LMNAMAPTGAAHTTALDH1A1 | |
| SCHEMBL3294994 | 0.79 | ALDH1A1 (0.59) | LMNAMAPTHTTALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4431663-A | ANTIULCER AND NEUROLEPTIC AGENTS; ANTIEMETICS | SHIONOGI & CO., LTD. (JP) | 1984-02-14 | — | — | US | disclosed |
| US-4351770-A | Preparation of N(2-pyrrolidinylmethyl)2-methoxy-5-benzenesulfonamidobenzamides | SHIONOGI & CO., LTD. (JP) | 1982-09-28 | — | — | US | disclosed |
| US-4350635-A | ANTIEMETICS, NEUROLEPTIC AGENTS | SHIONOGI & CO., LTD. (JP) | 1982-09-21 | — | — | US | disclosed |
| US-4330472-A | Meta-sulfonamido-benzamide derivatives | SHIONOGI & CO., LTD. (JP) | 1982-05-18 | — | — | US | disclosed |
| US-4328155-A | ANTIEMETIC OR PSYCHOTROPIC AGENT | SHIONOGI & CO., LTD. (JP) | 1982-05-04 | — | — | US | disclosed |
| US-4328344-A | ANTIEMETIC | SHIONOGI & CO., LTD. (JP) | 1982-05-04 | — | — | US | disclosed |