Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11083977 | 0.90 | TNKS (0.50) | TNKSTARBP2MAOBNPC1RAB9A | |
| SCHEMBL11089384 | 0.87 | TNKS (0.53) | TNKSTARBP2NPC1ALDH1A1KMT2A | |
| SCHEMBL11085395 | 0.81 | HPGD (0.49) | TNKSGAAALOX5NPC1RAB9A | |
| SCHEMBL11083211 | 0.80 | NPC1 (0.50) | TNKSNPC1RAB9AALDH1A1HTT | |
| SCHEMBL11085385 | 0.77 | TNKS (0.53) | TNKSTARBP2NPC1ALDH1A1KMT2A | |
| SCHEMBL11088040 | 0.75 | MAOB (0.54) | TNKSGAATARBP2MAOBALOX5 | |
| SCHEMBL11086127 | 0.75 | GABRP (0.42) | TNKSGAANPC1ALDH1A1HSD17B10 | |
| SCHEMBL3105153 | 0.75 | NPC1 (0.67) | GAATARBP2ALOX5ALPLNPC1 | |
| SCHEMBL3788451 | 0.74 | SMN1; SMN2 (0.47) | TNKSGAATARBP2MAOBALOX5 | |
| SCHEMBL11087831 | 0.74 | GABRP (0.41) | TNKSGAANPC1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4471129-A | ANTIHISTAMINES | LILLY INDUSTRIES LIMITED (GB) | 1984-09-11 | — | — | US | disclosed |
| US-4448787-A | ANTIALLERGENS | LILLY INDUSTRIES LIMITED (GB) | 1984-05-15 | — | — | US | disclosed |
| US-4304728-A | 2,6-DIHYDROXY-2,5-HEXADIENOIC ACID DERIVATIVES, ANTIHISTAMINE INTERMEDIATES | LILLY INDUSTRIES LIMITED (GB) | 1981-12-08 | — | — | US | disclosed |