Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TNKS | O95271 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GCGR | P47871 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.43 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21638246 | 0.87 | TNKS (0.47) | SMN1; SMN2KDM4EALDH1A1HPGDTNKS | |
| SCHEMBL3409831 | 0.86 | MAOB (0.52) | SMN1; SMN2KDM4EALDH1A1HPGDTNKS | |
| SCHEMBL21638154 | 0.85 | RAB9A (0.49) | SMN1; SMN2KDM4EALDH1A1HPGDTNKS | |
| SCHEMBL21638123 | 0.84 | CYP4F2 (0.41) | SMN1; SMN2KDM4EALDH1A1HPGDTNKS | |
| SCHEMBL21638142 | 0.81 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDTNKSKMT2A | |
| SCHEMBL21638185 | 0.80 | ALDH1A1 (0.45) | KDM4EALDH1A1HPGDTNKSGAA | |
| SCHEMBL3105153 | 0.77 | NPC1 (0.67) | SMN1; SMN2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL24824195 | 0.77 | KDM4E (0.41) | KDM4EALDH1A1HPGDTNKSHSD17B10 | |
| SCHEMBL11085508 | 0.74 | TNKS (0.48) | SMN1; SMN2KDM4EALDH1A1HPGDTNKS | |
| SCHEMBL23965786 | 0.74 | PRKD3 (0.43) | SMN1; SMN2KDM4EALDH1A1TNKSKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010133973-A1 | 1,4 DIHYDROPYRIDINE DERIVATIVES AND THEIR USES | UNIVERSITE LILLE 2 DROIT ET SANTE (FR) | 2010-11-25 | — | — | WO | disclosed |