Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 7/20 | 0.65 |
| ▸ | MMP1 | P03956 | 7/20 | 0.54 |
| ▸ | MMP2 | P08253 | 5/20 | 0.54 |
| ▸ | MMP3 | P08254 | 4/20 | 0.54 |
| ▸ | MMP9 | P14780 | 3/20 | 0.53 |
| ▸ | MMP8 | P22894 | 3/20 | 0.53 |
| ▸ | MMP7 | P09237 | 2/20 | 0.53 |
| ▸ | FCER2 | P06734 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 2/20 | 0.53 |
| ▸ | CTSB | P07858 | 2/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | CTSK | P43235 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22927767 | 0.94 | REN (0.62) | RENCTSSCTSBCTSLCTSK | |
| SCHEMBL24084059 | 0.91 | REN (0.64) | RENCTSSCTSBCTSLCTSK | |
| SCHEMBL22300786 | 0.91 | REN (0.64) | RENCTSSCTSBCTSLCTSK | |
| SCHEMBL30692461 | 0.91 | REN (0.64) | RENCTSSCTSBCTSLCTSK | |
| SCHEMBL30052641 | 0.90 | REN (0.62) | RENCTSSCTSBCTSLCTSK | |
| SCHEMBL26835279 | 0.90 | REN (0.62) | RENCTSSCTSBCTSLCTSK | |
| SCHEMBL22928874 | 0.90 | REN (0.71) | RENMMP1MMP2MMP3MMP9 | |
| SCHEMBL23463473 | 0.89 | REN (0.69) | RENCTSSCTSBCTSLCTSK | |
| SCHEMBL23447158 | 0.89 | REN (0.60) | RENCTSSCTSBCTSLCTSK | |
| SCHEMBL22301132 | 0.89 | REN (0.61) | RENCTSSCTSBCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4483988-A | Substituted derivatives of 4-t-alkoxycarbonyl-piperazin-2-ones | RICHARDSON MERRELL INC. (US) | 1984-11-20 | — | — | US | disclosed |
| US-4435571-A | 5-(Substituted benzyl)-6-oxo-2-piperazine carboxylic acids and esters | RICHARDSON MERRELL INC. (US) | 1984-03-06 | — | — | US | disclosed |
| US-4341698-A | Enkaphalin derivatives | RICHARDSON-MERRELL INC. (US) | 1982-07-27 | — | — | US | disclosed |