Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 10/20 | 0.60 |
| ▸ | CTSS | P25774 | 4/20 | 0.55 |
| ▸ | CTSK | P43235 | 3/20 | 0.55 |
| ▸ | CTSB | P07858 | 2/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23447618 | 0.92 | REN (0.52) | RENCTSSCTSKCTSBCTSL | |
| SCHEMBL22026259 | 0.89 | CTSS (0.64) | RENCTSSCTSKCTSBCTSL | |
| SCHEMBL26835279 | 0.89 | REN (0.62) | RENCTSSCTSKCTSBCTSL | |
| SCHEMBL11085637 | 0.89 | REN (0.65) | RENCTSSCTSKCTSBCTSL | |
| SCHEMBL22301082 | 0.88 | CTSS (0.54) | RENCTSSCTSKCTSBCTSL | |
| SCHEMBL23463473 | 0.88 | REN (0.69) | RENCTSSCTSKCTSBCTSL | |
| SCHEMBL22300786 | 0.88 | REN (0.64) | RENCTSSCTSKCTSBCTSL | |
| SCHEMBL24084059 | 0.88 | REN (0.64) | RENCTSSCTSKCTSBCTSL | |
| SCHEMBL30692461 | 0.88 | REN (0.64) | RENCTSSCTSKCTSBCTSL | |
| SCHEMBL21219323 | 0.88 | REN (0.68) | RENCTSSCTSKCTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021109351-A1 | POLYETHYLENE GLYCOL CONJUGATE DRUG, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 重庆阿普格雷生物科技有限公司 | 2021-06-10 | — | — | WO | disclosed |
| WO-2021104120-A1 | POLYETHYLENE GLYCOL CONJUGATE MEDICAMENT, PREPARATION METHOD THERFOR AND USE THEREOF | 重庆阿普格雷生物科技有限公司 | 2021-06-03 | — | — | WO | disclosed |