Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 10/20 | 0.62 |
| ▸ | CTSS | P25774 | 4/20 | 0.53 |
| ▸ | CTSB | P07858 | 3/20 | 0.53 |
| ▸ | CTSK | P43235 | 3/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11085637 | 0.94 | REN (0.65) | RENCTSSCTSBCTSKCTSL | |
| SCHEMBL22300786 | 0.93 | REN (0.64) | RENCTSSCTSBCTSKCTSL | |
| SCHEMBL30692461 | 0.93 | REN (0.64) | RENCTSSCTSBCTSKCTSL | |
| SCHEMBL26835279 | 0.92 | REN (0.62) | RENCTSSCTSBCTSKCTSL | |
| SCHEMBL30052641 | 0.92 | REN (0.62) | RENCTSSCTSBCTSKCTSL | |
| SCHEMBL24084059 | 0.91 | REN (0.64) | RENCTSSCTSBCTSKCTSL | |
| SCHEMBL23446207 | 0.90 | REN (0.60) | RENCTSSCTSBCTSKCTSL | |
| SCHEMBL22301132 | 0.89 | REN (0.61) | RENCTSSCTSBCTSKCTSL | |
| SCHEMBL26835283 | 0.88 | REN (0.58) | RENCTSSCTSBCTSKCTSL | |
| SCHEMBL16577986 | 0.88 | REN (0.58) | RENCTSSCTSBCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210147624-A1 | DEGRADABLE POLYETHYLENE GLYCOL DERIVATIVE | NOF CORPORATION (JP) | 2021-05-20 | — | — | US | disclosed |
| US-20210023231-A1 | DEGRADABLE POLYETHYLENE GLYCOL CONJUGATE | NOF CORPORATION (JP) | 2021-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210023231-A1 | DEGRADABLE POLYETHYLENE GLYCOL CONJUGATE | LNPEP, CD68, CD4 | REN 1634/4885CTSS 38/4885CTSB 28/4885 |
| US-20210147624-A1 | DEGRADABLE POLYETHYLENE GLYCOL DERIVATIVE | LNPEP, CD68, VMP1 | REN 1861/4885CTSS 42/4885CTSB 81/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.