Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CXCL8 | P10145 | 4/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.36 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.36 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.36 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11092982 | 0.88 | — | — | |
| SCHEMBL11090380 | 0.76 | — | — | |
| SCHEMBL7583347 | 0.76 | AKR1B1 (0.58) | AKR1B1PTGS2ABCB11PTGS1LMNA | |
| SCHEMBL11195204 | 0.74 | G6PD (0.40) | LMNATDP1HPGDMMP2MMP9 | |
| SCHEMBL2209914 | 0.73 | CD44 (0.35) | TDP1CYP2C9HPGDCYP2C19 | |
| SCHEMBL11094485 | 0.72 | CYP3A4 (0.50) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL25941101 | 0.72 | AKR1B1 (0.53) | AKR1B1PTGS2ABCB11PTGS1TDP1 | |
| SCHEMBL1000848 | 0.71 | PTGS2 (0.53) | AKR1B1PTGS2ABCB11PTGS1LMNA | |
| SCHEMBL28287356 | 0.70 | AKR1B1 (0.67) | AKR1B1PTGS2ABCB11PTGS1LMNA | |
| SCHEMBL11051064 | 0.69 | AKR1B1 (0.50) | AKR1B1PTGS2ABCB11PTGS1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472433-A | Phenoxyphenyl acetic acids and their medicinal use | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0008226-A2 | Phenyl-alkanoic acid derivatives, the preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-02-20 | — | — | EP | disclosed |