Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.48 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1000848 | 0.89 | PTGS2 (0.53) | AKR1B1PTGS2ABCB11PTGS1LMNA | |
| SCHEMBL28287356 | 0.87 | AKR1B1 (0.67) | AKR1B1PTGS2ABCB11PTGS1LMNA | |
| SCHEMBL9614495 | 0.87 | AKR1B1 (0.50) | AKR1B1PTGS2ABCB11PTGS1LMNA | |
| SCHEMBL16396604 | 0.86 | PTGS2 (0.58) | AKR1B1PTGS2ABCB11PTGS1LMNA | |
| SCHEMBL16397052 | 0.86 | AKR1B1 (0.57) | AKR1B1PTGS2ABCB11PTGS1LMNA | |
| SCHEMBL6241910 | 0.86 | ABCB11 (0.62) | AKR1B1PTGS2ABCB11PTGS1LMNA | |
| SCHEMBL2729571 | 0.86 | CXCL8 (0.53) | AKR1B1PTGS2ABCB11PTGS1LMNA | |
| SCHEMBL16396968 | 0.86 | PTGS2 (0.54) | AKR1B1PTGS2ABCB11PTGS1LMNA | |
| SCHEMBL19138018 | 0.85 | PTGS2 (0.47) | AKR1B1PTGS2ABCB11PTGS1LMNA | |
| SCHEMBL11095059 | 0.84 | CXCL8 (0.56) | AKR1B1PTGS2ABCB11PTGS1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979847-B1 | WATER-SOLUBLE TRISAZO COMPOUNDS, AQUEOUS INK COMPOSITION AND COLORED ARTICLE | NIPPON KAYAKU KK (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-6409810-B1 | STORAGE STABILITY; HIGH OPTICAL DENSITY; WATERPROOF AND LIGHT RESISTANCE; PENS; PRINTED IMAGES | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2002-06-25 | — | — | US | disclosed |
| EP-0979847-A1 | WATER-SOLUBLE TRISAZO COMPOUNDS, AQUEOUS INK COMPOSITION AND COLORED ARTICLE | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2000-02-16 | — | — | EP | disclosed |
| US-4225492-A | Water-soluble disazo dyestuffs, prepared from unsymmetrical heterocyclic diamines | CASSELLA AKTIENGESELLSCHAFT (DE) | 1980-09-30 | — | — | US | disclosed |
| US-4144231-A | Soluble trisazo dyestuffs containing a 2-phenyl-benzimidazolyl, -benzoxazolyl or -benzthiazolyl middle component | CASSELLA AKTIENGESELLSCHAFT (DE) | 1979-03-13 | — | — | US | disclosed |