Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11093901 | 0.84 | ALDH1A1 (0.36) | ALDH1A1LMNAKDM4EL3MBTL1NPC1 | |
| SCHEMBL11091373 | 0.82 | ADORA3 (0.40) | ALDH1A1KDM4EADORA2AADORA3MAPT | |
| SCHEMBL28056341 | 0.81 | KDM4E (0.46) | ALDH1A1LMNAKDM4EADORA2AADORA1 | |
| SCHEMBL28459504 | 0.80 | PTGES (0.40) | CYP2C9KMT2A | |
| SCHEMBL9502623 | 0.78 | ALDH1A1 (0.37) | ALDH1A1LMNAKDM4EL3MBTL1ADORA2A | |
| SCHEMBL11127349 | 0.77 | ALDH1A1 (0.37) | ALDH1A1LMNAKDM4EL3MBTL1MAPT | |
| Pyridate SCHEMBL53240 | 0.76 | SOAT1 (0.40) | ALDH1A1ADORA3MAPTCYP2C9NPSR1 | |
| Pyridate SCHEMBL9065928 | 0.76 | SOAT1 (0.40) | ALDH1A1ADORA3MAPTCYP2C9NPSR1 | |
| Pyridate SCHEMBL30750987 | 0.76 | SOAT1 (0.40) | ALDH1A1ADORA3MAPTCYP2C9NPSR1 | |
| Pyridate SCHEMBL9474519 | 0.76 | SOAT1 (0.40) | ALDH1A1ADORA3MAPTCYP2C9NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4478999-A | Process for the preparation of phenylpyridazine compounds | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1984-10-23 | — | — | US | disclosed |