SCHEMBL11086237

SCHEMBL11086237

CC(C)(C)N(C(=O)Oc1ccccc1)C(=O)Oc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.55
ATM Q13315 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
RAB9A P51151 4/20 0.50
KMT2A Q03164 4/20 0.50
MEN1 O00255 3/20 0.50
NPSR1 Q6W5P4 2/20 0.50
ALDH1A1 P00352 3/20 0.47
PKM P14618 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.44
NPC1 O15118 2/20 0.44
ELANE P08246 2/20 0.43
MAPT P10636 1/20 0.43
HTT P42858 1/20 0.43
NPY5R Q15761 1/20 0.42
PTGES O14684 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29096029 0.82 L3MBTL1 (0.53) L3MBTL1ATMTDP1RAB9AKMT2A
SCHEMBL27389053 0.82 L3MBTL1 (0.53) L3MBTL1ATMTDP1RAB9AKMT2A
SCHEMBL27613428 0.81 L3MBTL1 (0.52) L3MBTL1ATMTDP1RAB9AKMT2A
SCHEMBL11271302 0.78 L3MBTL1 (0.53) L3MBTL1ATMTDP1RAB9AKMT2A
SCHEMBL27535998 0.78 HTT (0.49) L3MBTL1ATMTDP1RAB9AKMT2A
SCHEMBL27766267 0.78 KMT2A (0.50) L3MBTL1ATMTDP1RAB9AKMT2A
SCHEMBL10984055 0.78 L3MBTL1 (0.39) L3MBTL1ATMTDP1RAB9AKMT2A
SCHEMBL30439056 0.77 L3MBTL1 (0.52) L3MBTL1ATMTDP1RAB9AKMT2A
Phenyl Dimethylcarbamate SCHEMBL491227 0.77 RAB9A (0.78) L3MBTL1ATMTDP1RAB9AKMT2A
SCHEMBL11212298 0.77 TDP1 (0.61) L3MBTL1ATMTDP1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4447635-A N-Substituted imido-dicarboxylic acid diaryl ester compounds and herbicide intermediates BAYER AKTIENGESELLSCHAFT (DE) 1984-05-08 US claimed
EP-0034750-B1 N-SUBSTITUTED IMIDODICARBOXYLIC ACID DIARYL ESTERS AND A PROCESS FOR THEIR PREPARATION BAYER AG (DE) 1984-01-18 EP claimed
US-4451406-A N-Substituted imido-dicarboxylic acid diaryl ester method of preparation BAYER AKTIENGESELLSCHAFT (DE) 1984-05-29 US disclosed
US-4447635-A N-Substituted imido-dicarboxylic acid diaryl ester compounds and herbicide intermediates BAYER AKTIENGESELLSCHAFT (DE) 1984-05-08 US disclosed