SCHEMBL27613428

SCHEMBL27613428

CC(C)(C)N(N)C(=O)Oc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.52
ATM Q13315 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
RAB9A P51151 3/20 0.47
KMT2A Q03164 3/20 0.47
NPSR1 Q6W5P4 2/20 0.47
MEN1 O00255 2/20 0.47
ELANE P08246 4/20 0.45
ALDH1A1 P00352 1/20 0.45
PKM P14618 1/20 0.45
PTGES O14684 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.41
NPC1 O15118 1/20 0.41
HTT P42858 1/20 0.41
MAPT P10636 2/20 0.41
LMNA P02545 1/20 0.41
NPY5R Q15761 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4724333 0.82 ESR1 (0.47) RAB9AKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL11086237 0.81 L3MBTL1 (0.55) L3MBTL1ATMTDP1RAB9AKMT2A
SCHEMBL29096029 0.79 L3MBTL1 (0.53) L3MBTL1ATMTDP1RAB9AKMT2A
SCHEMBL27389053 0.79 L3MBTL1 (0.53) L3MBTL1ATMTDP1RAB9AKMT2A
SCHEMBL11029662 0.79 TDP1 (0.57) L3MBTL1ATMTDP1RAB9AKMT2A
SCHEMBL27794411 0.77 L3MBTL1 (0.47) L3MBTL1ATMTDP1RAB9AKMT2A
SCHEMBL8779784 0.77 L3MBTL1 (0.47) L3MBTL1ATMTDP1RAB9AKMT2A
SCHEMBL27588519 0.76 TDP1 (0.59) L3MBTL1ATMTDP1RAB9AKMT2A
SCHEMBL11271302 0.76 L3MBTL1 (0.53) L3MBTL1ATMTDP1RAB9AKMT2A
SCHEMBL27766267 0.75 KMT2A (0.50) L3MBTL1ATMTDP1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1615284-A Method for forming carbon-carbon bond or carbon-heteroatom bond RHODIA CHIMIE SA (FR) 2005-05-11 CN disclosed