Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | BACE1 | P56817 | 1/20 | 0.54 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.52 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.52 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.52 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.52 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL658208 | 1.00 | ABCG2 (0.57) | ABCG2MAOBLMNAABCB1APP | |
| SCHEMBL31233224 | 0.91 | MAOA (0.63) | MAOBLMNAAPPMAPTSLC5A1 | |
| SCHEMBL657272 | 0.91 | CYSLTR1 (0.65) | ABCG2MAOBAPPMAPTGSK3B | |
| SCHEMBL30382955 | 0.91 | MAOA (0.63) | MAOBLMNAAPPMAPTSLC5A1 | |
| SCHEMBL25198653 | 0.91 | MAOA (0.63) | MAOBLMNAAPPMAPTSLC5A1 | |
| SCHEMBL25202012 | 0.91 | MAOB (0.59) | ABCG2MAOBAPPGSK3BBACE1 | |
| SCHEMBL31233096 | 0.91 | MAOB (0.59) | ABCG2MAOBAPPGSK3BBACE1 | |
| SCHEMBL25221855 | 0.91 | MAOA (0.63) | MAOBLMNAAPPMAPTSLC5A1 | |
| SCHEMBL657273 | 0.91 | CYSLTR1 (0.65) | ABCG2MAOBAPPMAPTGSK3B | |
| SCHEMBL9577552 | 0.87 | ALDH1A1 (0.61) | LMNAMAPTSGMS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3437640-B1 | AGENT FOR TREATING SYNUCLEINOPATHY | UNIV TOHOKU (JP) | 2021-11-24 | — | — | EP | disclosed |
| US-10709688-B2 | Agent for treating synucleinopathy | TOHOKU UNIVERSITY (JP) | 2020-07-14 | — | — | US | disclosed |
| US-20190125726-A1 | AGENT FOR TREATING SYNUCLEINOPATHY | TOHOKU UNIVERSITY (JP) | 2019-05-02 | — | — | US | disclosed |
| EP-3437640-A1 | SYNUCLEINOPATHY THERAPEUTIC MEDICATION | Tohoku University (JP) | 2019-02-06 | — | — | EP | disclosed |
| EP-2349999-B1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIV SAARLAND (DE) | 2016-01-27 | — | — | EP | disclosed |
| US-8912186-B2 | Allosteric protein kinase modulators | UNIVERSITAET DES SAARLANDES (DE) | 2014-12-16 | — | — | US | disclosed |
| US-20120046307-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIVERSITAET DES SAARLANDES (DE) | 2012-02-23 | — | — | US | disclosed |
| EP-2349999-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | Universität des Saarlandes (DE) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010043711-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIVERSITAET DES SAARLANDES (DE) | 2010-04-22 | — | — | WO | disclosed |
| EP-2177510-A1 | Allosteric protein kinase modulators | Universität des Saarlandes (DE) | 2010-04-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10709688-B2 | Agent for treating synucleinopathy | SNCA, PARK7, SYNJ1 | ABCG2 3730/4885MAOB 1106/4885LMNA 2568/4885 |
| US-20120046307-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | AURKC, AURKA, AURKB | ABCG2 735/4885MAOB 4512/4885LMNA 3119/4885 |
| US-20190125726-A1 | AGENT FOR TREATING SYNUCLEINOPATHY | SNCA, PARK7, SYNJ1 | ABCG2 3730/4885MAOB 1106/4885LMNA 2568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.