Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | LIPE | Q05469 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9449107 | 0.82 | HCRTR1 (0.53) | HTTGAAMEN1KMT2ALMNA | |
| SCHEMBL9660382 | 0.82 | ALDH1A1 (0.38) | HTTMEN1KMT2ALMNAMAPT | |
| SCHEMBL11086253 | 0.81 | NPC1 (0.60) | SGMS2NPC1HTTGAAMEN1 | |
| Water SCHEMBL11090686 | 0.80 | NPC1 (0.58) | SGMS2NPC1HTTGAAMEN1 | |
| SCHEMBL6949956 | 0.78 | SGMS2 (0.55) | SGMS2NPC1HTTGAAMEN1 | |
| SCHEMBL14028219 | 0.78 | SGMS2 (0.55) | SGMS2NPC1HTTGAAMEN1 | |
| SCHEMBL6949961 | 0.78 | SGMS2 (0.55) | SGMS2NPC1HTTGAAMEN1 | |
| SCHEMBL112903 | 0.77 | SGMS2 (0.66) | SGMS2NPC1HTTGAAKMT2A | |
| SCHEMBL29433417 | 0.77 | SGMS2 (0.66) | SGMS2NPC1HTTGAAKMT2A | |
| SCHEMBL9696207 | 0.77 | SGMS2 (0.66) | SGMS2NPC1HTTGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647632-A1 | NOVEL BENZODIAZEPINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1995-04-12 | — | — | EP | disclosed |