Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11096167 | 0.95 | CYP3A4 (0.31) | CYP3A4ALDH1A1TSHRUSP2CHRM1 | |
| SCHEMBL11080712 | 0.94 | CTSS (0.38) | CTSLCTSSCYP3A4ALDH1A1TSHR | |
| SCHEMBL11082041 | 0.84 | PTGS1 (0.36) | CYP3A4ALDH1A1USP2CHRM1PTGS1 | |
| SCHEMBL11082044 | 0.84 | PTGS1 (0.36) | CYP3A4ALDH1A1USP2CHRM1PTGS1 | |
| SCHEMBL11076132 | 0.83 | CTSS (0.41) | CTSLCTSSCYP3A4ATMBACE1 | |
| SCHEMBL11080922 | 0.83 | CTSS (0.43) | CTSLCTSSPTGS1ATMBACE1 | |
| SCHEMBL11080150 | 0.80 | ELANE (0.30) | PTGS1 | |
| SCHEMBL11080145 | 0.80 | ELANE (0.30) | PTGS1 | |
| SCHEMBL11080033 | 0.80 | CTSS (0.40) | CTSLCTSSCYP3A4ALDH1A1TSHR | |
| SCHEMBL11079896 | 0.79 | MAPT (0.39) | CYP3A4TSHRUSP2CHRM1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4429128-A | CARBAPENICILLINS, THIENAMYCINS, BACTERICIDES | PFIZER INC. (US) | 1984-01-31 | — | — | US | disclosed |
| US-4348264-A | Photocatalyzed process for producing carbapenams and carbapen-2-ems | PFIZER INC. (US) | 1982-09-07 | — | — | US | disclosed |