Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14369835 | 0.84 | ATM (0.68) | ATMKDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL4441360 | 0.83 | SMN1; SMN2 (0.73) | ATMKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL501199 | 0.83 | ATM (0.73) | ATMKDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL8489898 | 0.82 | ATM (0.77) | ATMKDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL10174568 | 0.81 | ATM (0.75) | ATMKDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL14369836 | 0.81 | ATM (0.75) | ATMKDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL11081554 | 0.80 | ATM (0.97) | ATMKDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL5214308 | 0.80 | HRH3 (0.72) | KDM4EALDH1A1HPGDSMN1; SMN2GAA | |
| SCHEMBL11201848 | 0.79 | ATM (1.00) | ATMKDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL24177835 | 0.78 | ATM (0.70) | ATMKDM4EALDH1A1HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443603-A | PROTEOLYTIC ENZYME INHIBITORS | KOWA COMPANY LIMITED (JP) | 1984-04-17 | — | — | US | disclosed |
| EP-0071433-A1 | Medicine for the treatment of diabetes | KOWA COMPANY, LTD. (JP) | 1983-02-09 | — | — | EP | disclosed |
| EP-0067561-A2 | Piperazine derivatives and processes for producing them | KOWA COMPANY, LTD. (JP) | 1982-12-22 | — | — | EP | disclosed |