Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | PRNP | P04156 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PFKFB4 | Q16877 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11086761 | 0.81 | GAA (0.36) | GAAMEN1KMT2ALMNAMAPT | |
| SCHEMBL11086756 | 0.81 | GAA (0.36) | GAAMEN1KMT2ALMNAMAPT | |
| SCHEMBL2889379 | 0.80 | GPR35 (0.44) | RXFP1PRNPPDE10AEDNRA | |
| SCHEMBL23532121 | 0.79 | MEN1 (0.50) | GAAMEN1KMT2ALMNAMAPT | |
| SCHEMBL10980470 | 0.79 | LMNA (0.36) | MIFGAAMEN1KMT2ALMNA | |
| SCHEMBL10987314 | 0.74 | CHRNA7 (0.42) | GAALMNAMAPTALDH1A1KDM4E | |
| SCHEMBL10980463 | 0.72 | SLC9A1 (0.52) | ALDH1A1POLB | |
| SCHEMBL6363655 | 0.72 | POLB (0.40) | KMT2ALMNAPOLBRAB9AIL2 | |
| SCHEMBL4997470 | 0.71 | PTPN1 (0.42) | MIFKMT2AALDH1A1TSHRRAB9A | |
| SCHEMBL11084705 | 0.70 | KMT2A (0.34) | GAAMEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482553-A | ANTIBIOTICS, BACTERICIDES | ELI LILLY AND COMPANY (US) | 1984-11-13 | — | — | US | disclosed |
| EP-0122156-A2 | Improvements in or relating to benzothienylglycyl cephalosporin derivatives | ELI LILLY AND COMPANY (US) | 1984-10-17 | — | — | EP | disclosed |