SCHEMBL1108685

SCHEMBL1108685

COc1ccc(Cc2ccc(O)c(C(C)=O)c2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.54
CYP3A4 P08684 2/20 0.54
HPGD P15428 2/20 0.54
MAPK1 P28482 1/20 0.54
KLKB1 P03952 1/20 0.53
CTSB P07858 1/20 0.53
MMP9 P14780 1/20 0.53
DNMT1 P26358 1/20 0.53
DNMT3B Q9UBC3 1/20 0.53
DNMT3L Q9UJW3 1/20 0.53
DNMT3A Q9Y6K1 1/20 0.53
MAOA P21397 2/20 0.52
MAOB P27338 2/20 0.52
HNF4A P41235 1/20 0.51
SAE1 Q9UBE0 1/20 0.50
UBA2 Q9UBT2 1/20 0.50
CALM1 P0DP23 1/20 0.49
MEN1 O00255 1/20 0.48
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13302505 0.87 KLKB1 (0.68) ALDH1A1HPGDKLKB1CTSBMMP9
SCHEMBL13539015 0.86 KDM4E (0.56) ALDH1A1CYP3A4HPGDKLKB1CTSB
SCHEMBL27523421 0.85 NPC1 (0.52) ALDH1A1CYP3A4HPGDKLKB1CTSB
SCHEMBL13197956 0.83 KLKB1 (0.59) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL7958354 0.82 HNF4A (0.75) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL9003347 0.81 KLKB1 (0.62) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL312754 0.81 ALDH1A1 (0.72) ALDH1A1CYP3A4HPGDMAPK1MAOA
SCHEMBL29445806 0.81 ALDH1A1 (0.72) ALDH1A1CYP3A4HPGDMAPK1MAOA
SCHEMBL13427766 0.81 KLKB1 (0.56) MAPK1KLKB1CTSBMMP9DNMT1
SCHEMBL15831652 0.77 ALDH1A1 (0.56) ALDH1A1HPGDMMP9SAE1UBA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8178702-B2 Composition, method of authenticating, methods of making authenticatable compositions, authenticatable articles made there from SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-05-15 US disclosed
US-8153239-B2 Polycarbonate resin composition and heat ray shielding molded product MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2012-04-10 US disclosed
US-7635778-B2 For example, 3-ethylcarbonate-2-(4-(3-ethylcarbonate-4-oxo-4H-chromen-2-yl)phenyl)-4H-chromen-4-one; authentication markers for use in data storage media substrates SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-12-22 US disclosed
US-20090136730-A1 Polycarbonate Resin Composition and Heat Ray Shielding Molded Product MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2009-05-28 US disclosed
US-20080265176-A1 COMPOSITION, METHOD OF AUTHENTICATING, METHODS OF MAKING AUTHENTICATABLE COMPOSITIONS, AUTHENTICATABLE ARTICLES MADE THERE FROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2008-10-30 US disclosed
US-7419762-B2 Short life of optical device; reduced reflection; multilayer with reflective layer, oxygen penetrable ultraviolet radiation layers GENERAL ELECTRIC COMPANY (US) 2008-09-02 US disclosed
US-7271235-B2 Branched aromatic polycarbonate and its production method MITSUBISHI CHEMICAL CORPORATION (JP) 2007-09-18 US disclosed
US-7226719-B2 Limited play data storage media and coating formulations thereon GENERAL ELECTRIC COMPANY (US) 2007-06-05 US disclosed
US-7223520-B2 Limited play optical media device with barrier layers GENERAL ELECTRIC COMPANY (US) 2007-05-29 US disclosed
US-20070048664-A1 Coating formulation for limited play data storage media SABIC INNOVATIVE PLASTICS IP B.V. 2007-03-01 US disclosed
US-7175086-B2 Authentication system, data device, and methods for using the same GENERAL ELECTRIC COMPANY (US) 2007-02-13 US disclosed
US-7169615-B2 Method of authenticating polymers, authenticatable polymers, methods of making authenticatable polymers and authenticatable articles, and articles made there from GENERAL ELECTRIC COMPANY (US) 2007-01-30 US disclosed
US-7157129-B2 Method for making highly colored DVDs GENERAL ELECTRIC COMPANY (US) 2007-01-02 US disclosed