SCHEMBL312754

SCHEMBL312754

COc1ccc(O)c(C(C)=O)c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.72
HPGD P15428 4/20 0.72
CYP3A4 P08684 2/20 0.72
MAPK1 P28482 2/20 0.72
NPC1 O15118 4/20 0.58
RAB9A P51151 4/20 0.58
MEN1 O00255 5/20 0.55
KMT2A Q03164 5/20 0.55
KDM4E B2RXH2 4/20 0.55
MAPT P10636 4/20 0.55
SMN1; SMN2 Q16637 4/20 0.55
HSD17B10 Q99714 3/20 0.55
LMNA P02545 2/20 0.55
TP53 P04637 2/20 0.55
ALOX12 P18054 2/20 0.55
HTT P42858 2/20 0.55
ALOX15 P16050 3/20 0.54
CYP1A2 P05177 1/20 0.54
PGR P06401 1/20 0.54
ADORA3 P0DMS8 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29445806 1.00 ALDH1A1 (0.72) ALDH1A1HPGDCYP3A4MAPK1NPC1
SCHEMBL28093168 0.86 RAB9A (0.71) ALDH1A1HPGDCYP3A4MAPK1NPC1
SCHEMBL28548926 0.85 HPGD (0.58) ALDH1A1HPGDCYP3A4MAPK1NPC1
SCHEMBL20286467 0.84 MAOB (0.54) ALDH1A1HPGDCYP3A4MAPK1NPC1
SCHEMBL1986986 0.84 ALDH1A1 (0.61) ALDH1A1HPGDCYP3A4MAPK1NPC1
Paeonol SCHEMBL3710243 0.84 HPGD (1.00) ALDH1A1HPGDCYP3A4MAPK1NPC1
SCHEMBL128781 0.84 CA1 (0.61) ALDH1A1HPGDCYP3A4MAPK1NPC1
SCHEMBL29431885 0.84 CA1 (0.61) ALDH1A1HPGDCYP3A4MAPK1NPC1
Paeonol SCHEMBL29349833 0.84 HPGD (1.00) ALDH1A1HPGDCYP3A4MAPK1NPC1
SCHEMBL6856233 0.84 NPC1 (0.58) ALDH1A1HPGDCYP3A4MAPK1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 599 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119528857-A Synthesis method of 5-methoxy-3-benzofuranone 上海毕臣生化科技有限公司 2025-02-28 CN claimed
CN-114956978-B Microwave synthesis process of 2-hydroxy-5-methoxy acetophenone 重庆康普化学工业股份有限公司 2023-06-27 CN claimed
CN-116239622-A ER beta targeting hydrogen peroxide responsive near infrared fluorescent probe and preparation method and application thereof 武汉大学 2023-06-09 CN claimed
CN-114956978-A Microwave synthesis process of 2-hydroxy-5-methoxyacetophenone 重庆康普化学工业股份有限公司 2022-08-30 CN claimed
CN-107082789-B Method for preparing organic phosphate compound by efficiently esterifying P (O) -OH-containing compound and phenol 湖南理工学院 2020-08-28 CN claimed
CN-111187051-A Autoclaved aerated concrete block brick utilizing construction waste 佛冈豪鑫环保建材有限公司 2020-05-22 CN claimed
EP-0674233-B1 Recording sheets XEROX CORP (US) 2000-05-24 EP claimed
EP-0674233-A2 Recording sheets XEROX CORPORATION (US) 1995-09-27 EP claimed
CN-122029153-A Aromatic hydrocarbon receptor modulator compound, and preparation method and application thereof 德明药泰生物技术(深圳)有限公司 2026-05-12 CN disclosed
US-20260092045-A1 SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS WILMINGTON TRUST, NATIONAL ASSOCIATION 2026-04-02 US disclosed
US-20250163044-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-05-22 US disclosed
US-20250163013-A1 TREATMENT OF GENITOURINARY SYNDROME OF MENOPAUSE NORDEEN, Steven 2025-05-22 US disclosed
CN-116514788-B Chromone mTOR inhibitor, and pharmaceutical composition and application thereof 贵州医科大学 2025-05-13 CN disclosed
EP-4549424-A1 NEW LITHIUM EXTRACTING AGENT AND LIQUID ORGANIC MIXTURE THEREOF, AND METHOD FOR EXTRACTING LITHIUM BY MEANS OF EXTRACTION Beijing Salt Lake Technology Development Company Limited (CN) 2025-05-07 EP disclosed
US-4307020-A REACTING AN 0-HYDROXYACETOPHENONE WITH A GLYOXYLIC ACID BAYER AKTIENGESELLSCHAFT (DE) 1981-12-22 US disclosed
US-4285965-A FUNGICIDES AND INSECTICIDES FOR PLANTS BAYER AKTIENGESELLSCHAFT (DE) 1981-08-25 US disclosed
US-4281012-A HYPOLIPEMIC ACTIVITY ROUSSEL UCLAF (FR) 1981-07-28 US disclosed
EP-0000377-B1 PROCESS FOR THE PREPARATION OF CHROMONE DERIVATIVES, NEW CHROMONE DERIVATIVES AND THEIR USE AS PLANT-PROTECTING AGENTS BAYER AG (DE) 1981-01-21 EP disclosed
US-4189498-A FUNGICIDES, ARTHROPODICIDES BAYER AKTIENGESELLSCHAFT (DE) 1980-02-19 US disclosed
US-4002423-A Benzofuran derivatives process for their preparation and their use as optical brighteners HOECHST AKTIENGESELLSCHAFT (DT) 1977-01-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092045-A1 SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS TFPI, F3, BTK ALDH1A1 3179/4885HPGD 3409/4885CYP3A4 433/4885
US-20250163044-A1 COMPOUNDS NLN, SLC18A2, PYGB ALDH1A1 981/4885HPGD 694/4885CYP3A4 759/4885
US-20250163013-A1 TREATMENT OF GENITOURINARY SYNDROME OF MENOPAUSE SHBG, GSS, GPER1 ALDH1A1 2426/4885HPGD 58/4885CYP3A4 2315/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.