SCHEMBL1108699

SCHEMBL1108699

Cc1ccc(-c2cc(C)c(-c3ccc(C)cc3)c3nsnc23)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 4/20 0.39
▸ MEN1 O00255 3/20 0.34
▸ KMT2A Q03164 3/20 0.34
▸ MAPT P10636 3/20 0.34
▸ TSHR P16473 3/20 0.34
▸ NPSR1 Q6W5P4 2/20 0.34
▸ USP2 O75604 1/20 0.34
▸ GAA P10253 1/20 0.34
▸ ENPP1 P22413 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.32
▸ NPC1 O15118 1/20 0.32
▸ RAB9A P51151 1/20 0.32
▸ ALDH1A1 P00352 3/20 0.32
▸ ALOX12 P18054 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.31
▸ XBP1 P17861 1/20 0.31
▸ MAPK1 P28482 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ MAOA P21397 1/20 0.31
▸ MAOB P27338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14300642 0.84 LMNA (0.36) LMNAMEN1KMT2AMAPTNPSR1
SCHEMBL3564833 0.84 KIF11 (0.36) LMNAMEN1KMT2AMAPTTSHR
SCHEMBL18464126 0.82 HSP90AA1 (0.36) LMNAMEN1KMT2AMAPTTSHR
SCHEMBL23665468 0.80 LMNA (0.36) LMNAMEN1KMT2AMAPTTSHR
SCHEMBL14493024 0.79 CNR2 (0.33) LMNAMAPTNPC1RAB9AMAPK1
SCHEMBL862821 0.79 COMT (0.40) LMNAMEN1KMT2AMAPTTSHR
SCHEMBL862603 0.77 SENP1 (0.35) LMNAMEN1KMT2AMAPTTSHR
SCHEMBL20806202 0.77 COMT (0.39) LMNAMEN1KMT2AMAPTTSHR
SCHEMBL13958188 0.77 LMNA (0.42) LMNAMEN1KMT2AMAPTTSHR
SCHEMBL14495809 0.76 CNR2 (0.32) LMNAMAPTHSD17B10NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9179518-B2 Light emissive device CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2015-11-03 — — US disclosed
US-9136477-B2 Light emissive device CDT OXFORD LIMITED (GB) 2015-09-15 — — US disclosed
US-9028715-B2 Compositions and methods for manufacturing light-emissive devices CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2015-05-12 — — US disclosed
US-8981365-B2 Organic light emissive device comprising a trilayer cathode including a layer comprising sodium fluoride CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2015-03-17 — — US disclosed
US-8878163-B2 Light-emitting device and 9.9 biphenyl fluorene materials therefor CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2014-11-04 — — US disclosed
US-8648334-B2 Organic light emissive device comprising a trilayer cathode CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2014-02-11 — — US disclosed
US-8440325-B2 Electronic device CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2013-05-14 — — US disclosed
US-8399605-B2 Arylamine polymer CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2013-03-19 — — US disclosed
US-8389130-B2 Opto-electrical polymers and devices CDT OXFORD LIMITED (GB) 2013-03-05 — — US disclosed
US-8294341-B2 Organic electroluminescent device CDT OXFORD LIMITED (GB) 2012-10-23 — — US disclosed
US-20090227765-A1 Monomer for making a crosslinked polymer CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2009-09-10 — — US disclosed
US-20090174314-A1 Organic Light Emissive Device CDT OXFORD LIMITED (GB) 2009-07-09 — — US disclosed
US-20090167170-A1 Polymer CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2009-07-02 — — US disclosed
US-20090091247-A1 Organic Light-Emitting Device CDT OXFORD LIMITED (GB) 2009-04-09 — — US disclosed
US-20090072722-A1 LIGHT EMISSIVE DEVICE CTD OXFORD LIMITED (GB) 2009-03-19 — — US disclosed
US-20090045740-A1 Phosphorescent Organic Light Emissive Device CDT OXFORD LIMITED (GB) 2009-02-19 — — US disclosed
US-20090026933-A1 Organic Electroluminescent Device CDT OXFORD LIMITED (GB) 2009-01-29 — — US disclosed
US-20080315757-A1 Electronic Device CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2008-12-25 — — US disclosed
US-20080309229-A1 Arylamine Polymer CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2008-12-18 — — US disclosed
US-20080197768-A1 Light Emissive Device CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2008-08-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090227765-A1 Monomer for making a crosslinked polymer AR, RAD51, RAD1 LMNA 1992/4885MEN1 803/4885KMT2A 1422/4885
US-20090091247-A1 Organic Light-Emitting Device ARL1, RAD1, LAS1L LMNA 2227/4885MEN1 577/4885KMT2A 2696/4885
US-20080309229-A1 Arylamine Polymer NAT1, AR, AHR LMNA 3266/4885MEN1 2021/4885KMT2A 822/4885
US-20090167170-A1 Polymer AHR, PARG, PARN LMNA 646/4885MEN1 3761/4885KMT2A 341/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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