Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL11080640 | 0.89 | TGFBR1 (0.34) | SMN1; SMN2MAPK1ACHELMNAHTT | |
| SCHEMBL9494478 | 0.80 | SMN1; SMN2 (0.42) | SMN1; SMN2MAPK1ACHELMNAHTT | |
| SCHEMBL9494964 | 0.73 | GAA (0.39) | SMN1; SMN2MAPK1LMNAHTTGAA | |
| SCHEMBL15502152 | 0.72 | GAA (0.42) | SMN1; SMN2MAPK1LMNAHTTGAA | |
| SCHEMBL11187380 | 0.71 | SMN1; SMN2 (0.42) | SMN1; SMN2MAPK1LMNAHTTGAA | |
| SCHEMBL8415261 | 0.71 | SMN1; SMN2 (0.42) | SMN1; SMN2MAPK1LMNAHTTGAA | |
| SCHEMBL13681856 | 0.71 | SMN1; SMN2 (0.42) | SMN1; SMN2MAPK1LMNAHTTGAA | |
| SCHEMBL8836776 | 0.71 | GAA (0.46) | SMN1; SMN2MAPK1LMNAHTTGAA | |
| SCHEMBL9493882 | 0.70 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPK1ACHELMNAHTT | |
| SCHEMBL6240581 | 0.70 | ACHE (0.35) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4439585-A | Polyurethane diacrylate compositions as carrier for pharmacological agents | TYNDALE PLAINS-HUNTER, LTD. (US) | 1984-03-27 | — | — | US | disclosed |
| US-4439584-A | Gas and ion permeable membranes formed of polyurethane diacrylate compositions | TYNDALE PLAINS-HUNTER, LTD. (US) | 1984-03-27 | — | — | US | disclosed |
| US-4439583-A | Polyurethane diacrylate compositions useful in forming canulae | TYNDALE PLAINS-HUNTER, LTD. (US) | 1984-03-27 | — | — | US | disclosed |
| US-4424305-A | Surgical implants formed of polyurethane diacrylate compositions | TYNDALE PLAINS-HUNTER, LTD. (US) | 1984-01-03 | — | — | US | disclosed |
| US-4408023-A | HYDROPHILIC, RESILIENT | TYNDALE PLAINS-HUNTER, LTD. (US) | 1983-10-04 | — | — | US | disclosed |
| US-4359558-A | REACTING A POLYURETHANE WITH AN ETHER ESTER OF ACRYLIC OR METHACRYLIC ACID | TYNDALE PLAINS-HUNTER, LTD. (US) | 1982-11-16 | — | — | US | disclosed |