Methacrylic Acid

Methacrylic Acid

SCHEMBL11080640

C=C(C)C(=O)O.C=C(C)C(=O)O.CCOC(=O)NC(CO)OCCO

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
MAPK1 P28482 1/20 0.33
THRB P10828 1/20 0.32
MGAM O43451 1/20 0.32
GAA P10253 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
ATM Q13315 1/20 0.32
ACHE P22303 1/20 0.30
LMNA P02545 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11087203 0.89 SMN1; SMN2 (0.38) SMN1; SMN2MAPK1MGAMGAASI
SCHEMBL9494478 0.72 SMN1; SMN2 (0.42) SMN1; SMN2MAPK1MGAMGAASI
Methacrylic Acid SCHEMBL5067704 0.70 ALDH1A1 (0.50) THRBMGAMGAASIMGAM2
Methacrylic Acid SCHEMBL27953946 0.69 GAA (0.44) SMN1; SMN2MAPK1THRBMGAMGAA
Ethyl Hydroxycarbamate SCHEMBL8928166 0.69 GAA (0.44) SMN1; SMN2THRBMGAMGAASI
SCHEMBL15502152 0.69 GAA (0.42) SMN1; SMN2MAPK1MGAMGAASI
SCHEMBL14576140 0.68 TGFBR1 (0.50) TGFBR1THRBMGAMGAASI
Acetic Acid SCHEMBL9638139 0.68 SMN1; SMN2 (0.42) SMN1; SMN2MAPK1MGAMGAASI
Methacrylic Acid SCHEMBL27450169 0.68 THRB (0.56) SMN1; SMN2THRBMGAMGAASI
Methacrylic Acid SCHEMBL8928145 0.68 ACHE (0.49) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4439585-A Polyurethane diacrylate compositions as carrier for pharmacological agents TYNDALE PLAINS-HUNTER, LTD. (US) 1984-03-27 US disclosed
US-4439584-A Gas and ion permeable membranes formed of polyurethane diacrylate compositions TYNDALE PLAINS-HUNTER, LTD. (US) 1984-03-27 US disclosed
US-4439583-A Polyurethane diacrylate compositions useful in forming canulae TYNDALE PLAINS-HUNTER, LTD. (US) 1984-03-27 US disclosed
US-4424305-A Surgical implants formed of polyurethane diacrylate compositions TYNDALE PLAINS-HUNTER, LTD. (US) 1984-01-03 US disclosed
US-4408023-A HYDROPHILIC, RESILIENT TYNDALE PLAINS-HUNTER, LTD. (US) 1983-10-04 US disclosed
US-4359558-A REACTING A POLYURETHANE WITH AN ETHER ESTER OF ACRYLIC OR METHACRYLIC ACID TYNDALE PLAINS-HUNTER, LTD. (US) 1982-11-16 US disclosed